Abstract

In this work, the cubic Peng-Robinson and two versions of the SAFT (-HR and -VR Mie) equations of state are applied to study the solubility of six vitamin K-3 derivatives in supercritical carbon dioxide. For these molecules, most of their thermophysical properties are unknown, hence, group contribution methods are applied to estimate the needed properties involved in the computation of solubility as well as the parameters of the equations of state. The performance of the equations of state to describe bulk densities, as well as the ability to correlate the experimental solubility of the compounds and their relationship with the molecular structure is studied. It is found that all the equations of state describe acceptably the density in the supercritical region of interest, but the solubility prediction from the SAFT-VR Mie model presents the best performance. (C) 2020 Elsevier B.V. All rights reserved.