Synthesis of benzo[b]thiophene carboxamides connected to 4-arylpiperazines through a benzylic spacer: Potential Ligands with 5-HT1A binding affinity
Abstract
New benzothiophene arylpiperazine derivatives 8 (a-f) were synthesized as potential serotoninergic agents with 5-HT1A receptor affinity. Preparation of the derivatives was performed by treating N-[2-(chloromethyl)phenyl]-4,7- dimethoxybenzo[b]thiophene-2-carboxamide (7) with a series of substituted 4-arylpiperazines. Copyright © Taylor & Francis Group, LLC.
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Título según WOS: | Synthesis of benzo[b]thiophene carboxamides connected to 4-arylpiperazines through a benzylic spacer: Potential Ligands with 5-HT1A binding affinity |
Título según SCOPUS: | Synthesis of benzo[b]thiophene carboxamides connected to 4-arylpiperazines through a benzylic spacer: Potential ligands with 5-HT1A binding affinity |
Título de la Revista: | SYNTHETIC COMMUNICATIONS |
Volumen: | 37 |
Número: | 19-21 |
Editorial: | TAYLOR & FRANCIS INC |
Fecha de publicación: | 2007 |
Página de inicio: | 3559 |
Página final: | 3567 |
Idioma: | English |
URL: | http://www.tandfonline.com/doi/abs/10.1080/00397910701557499 |
DOI: |
10.1080/00397910701557499 |
Notas: | ISI, SCOPUS |