Synthesis of benzo[b]thiophene carboxamides connected to 4-arylpiperazines through a benzylic spacer: Potential Ligands with 5-HT1A binding affinity

Pessoa-Mahana H.; Acevedo R,; Araya-Maturana, R; Saitz C.; Pessoa-Mahana, CD

Abstract

New benzothiophene arylpiperazine derivatives 8 (a-f) were synthesized as potential serotoninergic agents with 5-HT1A receptor affinity. Preparation of the derivatives was performed by treating N-[2-(chloromethyl)phenyl]-4,7- dimethoxybenzo[b]thiophene-2-carboxamide (7) with a series of substituted 4-arylpiperazines. Copyright © Taylor & Francis Group, LLC.

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Título según WOS: Synthesis of benzo[b]thiophene carboxamides connected to 4-arylpiperazines through a benzylic spacer: Potential Ligands with 5-HT1A binding affinity
Título según SCOPUS: Synthesis of benzo[b]thiophene carboxamides connected to 4-arylpiperazines through a benzylic spacer: Potential ligands with 5-HT1A binding affinity
Título de la Revista: SYNTHETIC COMMUNICATIONS
Volumen: 37
Número: 19-21
Editorial: TAYLOR & FRANCIS INC
Fecha de publicación: 2007
Página de inicio: 3559
Página final: 3567
Idioma: English
URL: http://www.tandfonline.com/doi/abs/10.1080/00397910701557499
DOI:

10.1080/00397910701557499

Notas: ISI, SCOPUS