Oral Dexmedetomidine Promotes Non-rapid Eye Movement Stage 2 Sleep in Humans

Hobbs, Lauren; Marota, Sophia; Sheppard, Kimberly S.; Manoach, Dara S.; DiBiasio, Alan; Nguyen, Sarah

Abstract

Background: The administration of dexmedetomidine is limited to highly monitored care settings because it is only available for use in humans as intravenous medication. An oral formulation of dexmedetomidine may broaden its use to all care settings. The authors investigated the effect of a capsule-based solid oral dosage formulation of dexmedetomidine on sleep polysomnography.

Más información

Título según WOS: Oral Dexmedetomidine Promotes Non-rapid Eye Movement Stage 2 Sleep in Humans
Título de la Revista: ANESTHESIOLOGY
Volumen: 133
Número: 6
Editorial: LIPPINCOTT WILLIAMS & WILKINS
Fecha de publicación: 2020
Página de inicio: 1234
Página final: 1243
DOI:

10.1097/ALN.0000000000003567

Notas: ISI