Proyecto
 (2023)

New trisubstituted purine derivatives as potent inhibitors and PROTAC warheads against mutated Bcr-Abl and Btk: A combined strategy to target key proteins for the treatment of leukaemia

Salas, Cristian Osvaldo; Oyarzun Ampuero, Felipe; Castro-Alvarez, Alejandro; del Campo, Andrea; Espinosa-Bustos, Christian; Pérez-Castro Ramón Andrés

Más información

Fecha de publicación: 2023
Objetivos: This research is focused on the development and optimisation of novel purine derivatives targeting two kinases involved in leukaemia, from design, in vitro biological study to in vivo assays.
Instrumento: FONDECYT
Año de Inicio/Término: 2023-2026
Financiamiento/Sponsor: CONICYT
Rol del Usuario: COINVESTIGADOR(A)
DOI:

1231199