Modeling oxygen transport in surgical tissue transfer

Kao, Chiu-Yen; Green, J. Edward F.; Sutradhar, Alok; Friedman, Avner

Abstract

Reconstructive microsurgery is a clinical technique used to transfer large amounts of a patient's tissue from one location used to another in order to restore physical deformities caused by trauma, tumors, or congenital abnormalities. The trend in this field is to transfer tissue using increasingly smaller blood vessels, which decreases problems associated with tissue harvest but increases the possibility that blood supply to the transferred tissue may not be adequate for healing. It would thus be helpful to surgeons to understand the relationship between the tissue volume and blood vessel diameter to ensure success in these operations. As a first step towards addressing this question, we present a simple mathematical model that might be used to predict successful tissue transfer based on blood vessel diameter, tissue volume, and oxygen delivery.

Más información

Título según WOS: ID WOS:000268178400050 Not found in local WOS DB
Título de la Revista: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volumen: 106
Número: 29
Editorial: NATL ACAD SCIENCES
Fecha de publicación: 2009
Página de inicio: 12091
Página final: 12096
DOI:

10.1073/pnas.0905037106

Notas: ISI