Article ISI SCOPUS
TETRAHEDRON LETTERS  (2008)

Synthesis of a new nitrogenated drimane derivative with antifungal activity

Zarraga, M.; Zarraga, AM; Rodríguez, B.; Pérez, C.; Paz, C; Paz, P; Sanhueza C.

Abstract

Drimane sesquiterpenes are highly valuable due to their strong biological activity. In this work, we report the enhanced antifungal activity of 11-guanidinodrimene, a new compound derived from drimenol. The binding of the guanidine group at the C-11 carbon increased the antifungal activity when tested against Candida albicans, one of the most commonly found human pathogens. © 2008 Elsevier Ltd. All rights reserved.

Más información

Título según WOS: Synthesis of a new nitrogenated drimane derivative with antifungal activity
Título según SCOPUS: Synthesis of a new nitrogenated drimane derivative with antifungal activity
Título de la Revista: TETRAHEDRON LETTERS
Volumen: 49
Número: 32
Editorial: PERGAMON-ELSEVIER SCIENCE LTD
Fecha de publicación: 2008
Página de inicio: 4775
Página final: 4776
Idioma: English
URL: http://linkinghub.elsevier.com/retrieve/pii/S004040390801006X
DOI:

10.1016/j.tetlet.2008.05.092
Notas: ISI, SCOPUS