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DPP9 Comes of Age: Highly Selective Inhibitors Promise New Therapeutic Opportunities
Abstract
Dipeptidyl peptidase-like protein 9 (DPP9) is emerging as a promising drug target for the treatment of hematological diseases. Two novel DPP9 inhibitors with nanomolar affinity and unprecedented selectivity to DPP9 over DPP8 have been discovered, paving the way for future progress in DPP9-mediated treatments. © 2023 American Chemical Society.
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| Título según WOS: | DPP9 Comes of Age: Highly Selective Inhibitors Promise New Therapeutic Opportunities |
| Título según SCOPUS: | DPP9 Comes of Age: Highly Selective Inhibitors Promise New Therapeutic Opportunities |
| Título de la Revista: | Journal of Medicinal Chemistry |
| Volumen: | 66 |
| Número: | 18 |
| Editorial: | American Chemical Society |
| Fecha de publicación: | 2023 |
| Página de inicio: | 12715 |
| Página final: | 12716 |
| Idioma: | English |
| URL: | 10.1021/acs.jmedchem.3c01631 |
| DOI: |
10.1021/acs.jmedchem.3c01631 |
| Notas: | ISI, SCOPUS - ISI |