Article ISI SCOPUS
ARCHIV DER PHARMAZIE  (2008)

Cytotoxic-antineoplastic derivatives of prenyl-1,2-naphthohydroquinone

Molinari, A; Oliva A.; Ojeda, C; del Corral, JMM; Castro MA; Cuevas, C; Feliciano, AS

Abstract

Several new prenyl-1,2-naphthohydroquinone derivatives have been prepared by chemical modifications of Diels-Alder products which were obtained from cycloaddition of α-myrcene to 1,2-benzoquinone and then evaluated in vitro for their cytotoxic activity against A-549 lung carcinoma, HT-29 colon carcinoma, and MB-231 breast adeno-carcinoma culture cells. Most of them exhibited GI50 values in the μM-concentration level. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.

Más información

Título según WOS: Cytotoxic-antineoplastic derivatives of prenyl-1,2-naphthohydroquinone
Título según SCOPUS: Cytotoxic-antineoplastic derivatives of prenyl-1,2-naphthohydroquinone
Título de la Revista: ARCHIV DER PHARMAZIE
Volumen: 341
Número: 5
Editorial: WILEY-V C H VERLAG GMBH
Fecha de publicación: 2008
Página de inicio: 301
Página final: 306
Idioma: English
URL: http://doi.wiley.com/10.1002/ardp.200700259
DOI:

10.1002/ardp.200700259
Notas: ISI, SCOPUS