Living-donor kidney graft ex vivo endoscopic nephrolithotomy with flexible instrument

Gallegos, Hector; Sepulveda, Francisca; Dominguez, Javier; Saez, Gerardo; Galdames, Elizabeth; Troncoso, Pablo

Abstract

Introduction: The finding of an asymptomatic stone in the study of a living kidney donor does not necessarily contraindicate donation, however, there is no consensus on the management of these cases. The use of a graft with lithiasis may represent a risk of recurrence in the remaining kidney in the donor and eventual obstructive complications in the transplanted kidney. The objective of this work is to present the usefulness of ureteroscopy (URS) to resolve lithiasis ex vivo before transplantation. Material and Methods: Donors with a small, asymptomatic kidney stone and with an analysis of lithogenic factors without relevant findings were considered to continue in the donation process. The kidney unit with stone was selected for nephrectomy. Results: Four donor kidneys underwent flexible URS after nephrectomy under hypothermic preservation conditions during bench preparation. The average time of the procedure was 35 minutes and the stone was extracted in all cases without incident. The transplant was carried out in the usual way and the evolution of the recipients was without complications and with excellent renal function. During follow-up, no recurrence of lithiasis was observed in donors or recipients. Conclusions: In this experience, the URS of the donor kidney was a feasible procedure and was not associated with adverse consequences for the graft. The main advantage of this procedure is to avoid the potential risk to the recipient of an obstructive graft complication.

Más información

Título según WOS: ID WOS:001163807400012 Not found in local WOS DB
Título de la Revista: REVISTA MEDICA DE CHILE
Volumen: 151
Número: 3
Editorial: Sociedad Médica de Santiago
Fecha de publicación: 2023
Página de inicio: 370
Página final: 374
Notas: ISI