Copper/Silver Bimetallic Nanoparticles Supported on Aluminosilicate Geomaterials as Antibacterial Agents

Cruces, Edgardo; Arancibia-Miranda, Nicolas; Manquian-Cerda, Karen; Perreault, Francois; Bolan, Nanthi; Ignacio Azocar, Manuel; Cubillos, Victor; Montory, Jaime; Angelica Rubio, Maria; Sarkar, Binoy

Abstract

This study aims to understand how properties of modified aluminosilicate geomaterials influence the antibacterial performance of nanocomposites when prepared with bimetallic nanoparticles (NPs). Copper/silver (Cu/Ag) bimetallic NPs were synthesized in the presence of imogolite (Imo), montmorillonite (Mtt), or zeolite (Zeo) using a simple onepot method and characterized for their crystal phases, micro- and nanomorphologies, particle size, elemental composition, and electrophoretic mobility. The antibacterial activity was evaluated through minimum inhibition concentration assays of NPs and nanocomposites for Gram (-) Escherichia coli and Gram (+) Staphylococcus aureus bacteria. Deposition of metallic Cu-0, Ag-0, and cuprite NPs was confirmed in Zeo_Cu/Ag and Imo_Cu/Ag nanocomposites, whereas only Cu-0 and Ag-0 were identified in Mtt_Cu/Ag. The bimetallic NPs were more uniformly distributed on Zeo and Mtt than Imo. Particle sizes of 28.1 +/- 5.0, 9.4 +/- 2.3, 10.1 +/- 1.7, and 12 +/- 1.3 nm were determined for Cu/Ag NPs, Imo_Cu/Ag, Mtt_Cu/Ag, and Zeo_Cu/Ag, respectively. The release rate of Cu and Ag ions from Zeo_Cu/Ag was higher than those of pristine Cu/Ag NPs and the other two nanocomposites. The antimicrobial action of bimetallic NPs and nanocomposites was dose-dependent in relation to the concentration of concerned materials and their stability in the medium. The physicochemical characteristics of Zeo resulted in a homogeneous distribution and low oxidation and agglomeration of Cu/Ag NPs, consequently increasing the antibacterial activity. Results of this study highlight the benefits of using a geomaterial support to achieve high antibacterial activity of bimetallic NPs, which could help reduce the consumption of pure Cu/Ag salts in NP-based antibacterial applications.

Más información

Título según WOS: Copper/Silver Bimetallic Nanoparticles Supported on Aluminosilicate Geomaterials as Antibacterial Agents
Título de la Revista: ACS APPLIED NANO MATERIALS
Volumen: 5
Número: 1
Editorial: AMER CHEMICAL SOC
Fecha de publicación: 2022
Página de inicio: 1472
Página final: 1483
DOI:

10.1021/acsanm.1c04031

Notas: ISI