White Adipose Tissue Dysfunction: Pathophysiology and Emergent Measurements
Abstract
White adipose tissue (AT) dysfunction plays an important role in the development of cardiometabolic alterations associated with obesity. AT dysfunction is characterized by the loss of the expansion capacity of the AT, an increment in adipocyte hypertrophy, and changes in the secretion profile of adipose cells, associated with accumulation of macrophages and inflammation. Since not all people with an excess of adiposity develop comorbidities, it is necessary to find simple tools that can evidence AT dysfunction and allow the detection of those people with the potential to develop metabolic alterations. This review focuses on the current pathophysiological mechanisms of white AT dysfunction and emerging measurements to assess its functionality.
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Título según WOS: | ID WOS:000968892000001 Not found in local WOS DB |
Título según SCOPUS: | ID SCOPUS_ID:85152336682 Not found in local SCOPUS DB |
Título de la Revista: | NUTRIENTS |
Volumen: | 15 |
Editorial: | MDPI |
Fecha de publicación: | 2023 |
DOI: |
10.3390/NU15071722 |
Notas: | ISI, SCOPUS |