Compact dynamic simulator of the human gastrointestinal system

Riquelme, Angeline; Sofia Estrugo; Villanueva, Francisca; Munoz-Gonzalez, Rodrigo; Rodrigo contreras; Ana batista

Abstract

A gastrointestinal simulator system includes a thermoregulated bath, two glass beakers situated within the thermoregulated water bath, and a pump. The beakers simulate the stomach and intestines and are coupled together using a tube. A sieve, positioned within the “stomach,” has a plurality of 2 mm holes on its surface to mimic in vivo conditions, where only particles smaller than 2 mm in diameter are transferred to the “intestines.” These collected particles move from “stomach” (specifically, from the sieve) to the “intestines” through the tube coupling the beakers. Cameras may be located inside the water bath for monitoring/recording of the digestion. Alerts, such as voice alerts, may be generated to notify users of any important information and instructions. After digestion, reports of the digestion are automatically generated and stored in a data repository. One or more users are notified that the reports are available for access.

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Fecha de publicación: 2023
DOI:

US20230237934A1