Abstract

An in vitro dynamic mouth model includes an upper jaw that includes a plurality of protuberances simulating human teeth, a lower jaw that is coupled with a rounded silicone pad simulating human tongue, and a mouth wall that encapsulates food sample(s) subjected to in vitro mastication such that the food sample remains within the mouth model. The mouth wall contains at least one hole that allows injection of simulated saliva fluid. As simulated chewing takes place, the injected fluid directly interacts with the food sample.