Diagnostic support in pediatric craniopharyngioma using deep learning

Castiglioni, Giovanni; Vallejos, Joaquin; Intriago, Jhon; Hernandez, Maria Isabel; Valenzuela, Samuel; Fernandez, Jose; Castro, Ignacio; Valenzuela, Sergio; Estevez, Pablo A.; Okuma, Cecilia

Abstract

PurposeWe studied a pediatric group of patients with sellar-suprasellar tumors, aiming to develop a convolutional deep learning algorithm for radiological assistance to classify them into their respective cohort.MethodsT1w and T2w preoperative magnetic resonance images of 226 Chilean patients were collected at the Institute of Neurosurgery Dr. Alfonso Asenjo (INCA), which were divided into three classes: healthy control (68 subjects), craniopharyngioma (58 subjects) and differential sellar/suprasellar tumors (100 subjects).ResultsThe PPV among classes was 0.828 +/- 0.039, and the NPV was 0.919 +/- 0.063. Also explainable artificial intelligence (XAI) was used, finding that structures that are relevant during diagnosis and radiological evaluation highly influence the decision-making process of the machine.ConclusionThis is the first experience of this kind of study in our institution, and it led to promising results on the task of radiological diagnostic support based on explainable artificial intelligence (AI) and deep learning models.

Más información

Título según WOS: ID WOS:001206042900003 Not found in local WOS DB
Título de la Revista: CHILDS NERVOUS SYSTEM
Volumen: 40
Número: 8
Editorial: Springer
Fecha de publicación: 2024
Página de inicio: 2295
Página final: 2300
DOI:

10.1007/s00381-024-06400-0

Notas: ISI