VCD Determination of the Absolute Configuration of Stypotriol

Munoz, MA; Areche, C; San Martin, A; Rovirosa, J; Joseph-Nathan, P

Abstract

The absolute configuration of the pentacyclic ichthyotoxin stypotriol, a constituent of Stypopodium zonale, was deduced to be 3S,5R,8R,9R,10S,13S,14S-(-) -1 by vibrational circular dichroism spectroscopy of the derived triacetate 2 in comparison to DFT B3LYP/DGDZVP calculations. Compound 2, C33H46O7 having 300 electrons, is the largest natural product successfully studied by VCD to date.

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Título según WOS: VCD Determination of the Absolute Configuration of Stypotriol
Título según SCOPUS: VCD determination of the absolute configuration of stypotriol
Título de la Revista: NATURAL PRODUCT COMMUNICATIONS
Volumen: 4
Número: 8
Editorial: SAGE PUBLICATIONS INC
Fecha de publicación: 2009
Página de inicio: 1037
Página final: 1040
Idioma: English
Notas: ISI, SCOPUS