Abstract

In this work, the ruggedness of several variables suspected influents on extraction of ethylated organotins (butyl-and phenyltins) by Solid Phase Microextraction in headspace mode (HS-SPME) was realized by using Gas Chromatography-Pulsed Flame Photometric detection (GC-PFPD). The influence of eight factors on SPME procedure was analyzed using an 11-factor, 12-experiment Plackett-Burman design on the chromatographic area normalized to either Tripropyltin or Diheptyltin area. After the results, the extraction of OTC by HS-SPME could be considered as rather robust as the factor effects were generally not significant or small when both internal standards were used.