It's About Timing: Contrasting the Metabolic Effects of Early vs. Late Time-Restricted Eating in Humans

Sepúlveda, Bernardita; Marin, Andrea; Burrows, Raquel; Sepulveda, Alejandro; Chamorro, Rodrigo

Abstract

Purpose of ReviewTime-restricted eating (TRE), a form of intermittent fasting, restricts feeding time across the day, imposing a daily 'eating window'. The time of day when the eating window occurs could result in differential metabolic effects. Here, we describe recent intervention studies in humans assessing the metabolic consequences of an early- (i.e., eating window starting in the early morning) vs. late (i.e., eating window starting after midday)-TRE protocol.Recent FindingsWell-controlled studies indicate that both TRE protocols effectively reduce body weight and improve altered glucose metabolism, lipid profile, inflammation, or blood pressure levels. An early-TRE (e-TRE) might have a further positive impact on improving blood glucose, insulin levels, and insulin resistance. However, the studies directly assessing the metabolic consequences of an early- vs. late-TRE have shown dissimilar findings, and more well-controlled clinical trials are needed on the metabolic benefits of these two types of TRE.SummaryEvidence suggests that an e-TRE might have enhanced metabolic results, particularly regarding glucose homeostasis. More long-term studies, including larger sample sizes, are needed to assess the metabolic, circadian, and adherence benefits, together with socio-cultural acceptance of both TRE approaches.

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Título según WOS: It's About Timing: Contrasting the Metabolic Effects of Early vs. Late Time-Restricted Eating in Humans
Título de la Revista: CURRENT NUTRITION REPORTS
Volumen: 13
Número: 2
Editorial: SPRINGERNATURE
Fecha de publicación: 2024
Página de inicio: 214
Página final: 239
DOI:

10.1007/s13668-024-00532-0

Notas: ISI