Abstract

Background: Nutritional status may be affected by eating behavior and circadian rhythms. These are regulated by the CLOCK gene, whose T alleles of SNP rs3749474T/C and A of SNP rs4864548A/G, have been associated with obesity in adults. Methods: 65 subjects were evaluated using the real-time PCR technique to determine whether they were carriers of the T allele of the SNP rs3749474T/C or the A of the SNP rs4864548A/G. Anthropometric measurements were made, and the TFEQ and Horne-Östberg questionnaires were applied. Results: Of the 65 subjects studied, 8 were carriers of the T allele of the SNP rs3749474T/C and 7 of the A of the SNP rs4864548A/G. The carriers of the A allele had higher average BMI values (26.58), waist circumference (89.57cm) and fat percentage (31.56%), with no statistically significant differences between them. No statistically significant differences were found regarding eating behavior. 66.67% of the total subjects presented an intermediate type chronotype. Conclusions: The carriers of the A allele of SNP rs4864548A/ G would have a greater potential to suffer problems associated with obesity, but studies with larger populations and with better gender parity are necessary, which allows to confirm this assertion.