Chemical and biological antioxidant activity evaluation of extracts from berries pomaces

Vergara-Castro, Mauricio; Soto-Maldonado, Carmen; Zuniga-Hansen, Maria Elvira; Arancibia-Diaz, Alejandra; Fuentes, Paloma; Altamirano, Claudia

Abstract

Berries and berries pomaces have a high content of antioxidant compounds, especially anthocyanins. This work evaluates the chemical (TPC, FRAP, DPPH, ABTS, and ORAC) and biological (assays of cytotoxicity and loss of mitochondrial membrane potential (Delta psi m) on HL60 and fibroblast cells) antioxidant capacity of hydroalcoholic and aqueous extracts from raspberry and maqui pomaces. Better chemical results were obtained with hydro- alcoholic extracts. Raspberry extract has better results than maqui extract, except for anthocyanin content and ORAC activity that was similar. A maximum of 75 % and 38 % of inhibition of HL60 cell growth, respectively, was observed with hydro- alcoholic and aqueous extracts at 0.15 mg/mL. Fibroblast growth was inhibited only with raspberry pomace extract. Mostly, extracts allow cell growth under oxidative conditions, observing a protective effect equivalent to using a reference antioxidant (based on Delta psi m).This study therefore lays the groundwork for the biological evaluation of the use of extracts of maqui and raspberry pomace, with particular attention to their possible anticancer properties.

Más información

Título según WOS: ID WOS:001435081900001 Not found in local WOS DB
Título de la Revista: APPLIED FOOD RESEARCH
Volumen: 5
Número: 1
Editorial: Elsevier
Fecha de publicación: 2025
DOI:

10.1016/j.afres.2025.100781

Notas: ISI