Cs2CO3-Catalyzed Rauhut-Currier-Type Reaction for the Synthesis of 2,3-Dihydrobenzo[b]oxepin Derivatives
Abstract
The synthesis of fused benzoxepines relies on the use of complex substrates and methodologies. Herein, we report our experimental and theoretical findings about an unprecedented Rauhut-Currier-type reaction catalyzed by Cs2CO3 to access these important compounds. The developed methodology avoids the use of phosphine- or amine-based catalysts and additives. The reaction can be performed under microwave irradiation and proceeds with complete chemoselectivity.
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Título según WOS: | Cs2CO3-Catalyzed Rauhut-Currier-Type Reaction for the Synthesis of 2,3-Dihydrobenzo[b]oxepin Derivatives |
Volumen: | 89 |
Número: | 22 |
Fecha de publicación: | 2024 |
Página de inicio: | 16401 |
Página final: | 16405 |
Idioma: | English |
DOI: |
10.1021/acs.joc.4c01544 |
Notas: | ISI |