TRITERPENOIDS FROM Azorella trifurcata (Gaertn.) Pers AND THEIR EFFECT AGAINST THE ENZYME ACETYLCHOLINESTERASE

Areche, C; Cejas, P; Thomas P.; San Martin, A; Astudillo, L; Gutiérrez M; Loyola, LA

Abstract

The inhibition of the enzyme acetylcholinesterase is considered as a strategy for the treatment of Alzheimer's disease, senile dementia, ataxia, and myasthenia gravis. Three lanostane- and two cycloartane-type triterpenes, together with, two mulinane-type diterpenes were isolated from, petroleum ether extract of the whole shrub of Azorella trifurcata (Gaertn.) Pers. Their effect on the enzyme acetylcholinesterase was assessed, as well. In addition, this is the first report of these triterpenes in the genus Azorella.

Más información

Título según WOS: TRITERPENOIDS FROM Azorella trifurcata (Gaertn.) Pers AND THEIR EFFECT AGAINST THE ENZYME ACETYLCHOLINESTERASE
Título según SCOPUS: Triterpenoids from Azorella trifurcata (Gaertn.) pers and their effect against the enzyme acetylcholinesterase
Título de la Revista: QUIMICA NOVA
Volumen: 32
Número: 8
Editorial: SOC BRASILEIRA QUIMICA
Fecha de publicación: 2009
Página de inicio: 2023
Página final: 2025
Idioma: English
Notas: ISI, SCOPUS