Abstract

This review provides an overview of the current research on prebiotics and their applications in animal nutrition and health. Various types of prebiotics are introduced and classified, with an analysis of agroindustrial residues as sources. The potential of prebiotics as substrates for the growth and/or activity of probiotic microorganisms, as well as their applications in animal feeds, were examined. This analysis also considered the health-promoting advantages linked to different production techniques and bioactive compounds. The mechanisms by which prebiotics alter gastrointestinal tract microbiota are discussed, specifically in terms of combating pathogenic bacteria and modulating immune cells in the gut. Investigations of the impact of prebiotics in both polygastric and monogastric animals are reported, highlighting their effects on the gut ecosystem and animal performance. This review concludes that agroindustrial residues are valuable sources of prebiotics that possess numerous beneficial health-promoting properties suitable for animal nutrition. These prebiotics can serve as a relevant substitute in the ongoing search for alternative strategies to prevent and control the presence of pathogenic bacteria in animals, particularly considering the restriction on antimicrobial growth promoters. However, further research is necessary to explore the interaction between prebiotics and probiotics in animal care and well-being, to establish systematic management of production and practical applications of these functional feed additives. (c) 2025 The Authors. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co. Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/bync-nd/4.0/).