Abstract

The synthesis of four ferrocenylphosphine-amino acid ligands, (S)-(η5-C5H4-PR2)Fe(η5-C5H4-AA) [R= Ph, AA= l-Glu(OMe)2: 5a’ R= Cy, AA= l-Glu(OMe)2: 5b’ R= Ph, AA= l-Pro(OMe): 5a’’ R= Cy, AA= l-Pro(OMe): 5b’’] through a new synthetic method is presented along with two solid-state X-ray crystal structures of the corresponding phosphine selenides 5a’’Se and 5b’’Se. Electronic and basicity properties of the ligands were evaluated through the synthesis of the corresponding phosphine selenides 5a’Se – 5b’’Se. Coordination capabilities of the ferrocenylphosphine-amino acid ligands with the p-cymene ruthenium dichloride dimer was evaluated, affording four neutral complexes, RuCl2(η6-C10H14){PR2-[(η5-C5H4)Fe(η5-C5H4-AA)]} [R= Ph, AA= l-Glu(OMe)2: 6a’ R= Cy, AA= l-Glu(OMe)2: 6b’ R= Ph, AA= l-Pro(OMe): 6a’’ R= Cy, AA= l-Pro(OMe): 6b’’] and three cationic complexes ⟨RuCl(NCMe)(η6-C10H14){PR2-[(η5-C5H4)Fe(η5-C5H4-AA)]}⟩SbF6 [R= Ph, AA= l-Glu(OMe)2: 7a’ R= Ph, AA= l-Pro(OMe): 7a’’ R= Cy, AA= l-Pro(OMe): 7b’’]. All new ligands and complexes were fully characterized by NMR spectroscopy, electrospray ionization mass spectrometry and their electrochemical properties were measured by cyclic voltammetry at a platinum disk electrode. © 2025