Article ISI SCOPUS
HEPATOLOGY  (2021)

Epigenome-Wide Analysis of Methylation Changes in the Sequence of Gallstone Disease, Dysplasia, and Gallbladder Cancer

Braegelmann, Johannes; Barahona Ponce, Carol; MARCELAIN-CUBILLOS, KATHERINE JENNY; Roessler, Stephanie; Goeppert, Benjamin; GALLEGOS-MENDEZ, IVAN MARCELO; COLOMBO-FLORES, ALICIA ANGELINA; SANHUEZA-LINARES, VERONICA ISABEL; Morales, Erik; RIVERA-LOPEZ, MARIA TERESA; DE TORO-CONSUAGRA, GONZALO ANDRES; ORTEGA-VASQUEZ, ALEJANDRO JAVIER; Müller, Bettina; ACUNA-MUNOZ, JACQUELINE; Scherer, Dominique; et. al.

Abstract

Background and Aims Gallbladder cancer (GBC) is a highly aggressive malignancy of the biliary tract. Most cases of GBC are diagnosed in low-income and middle-income countries, and research into this disease has long been limited. In this study we therefore investigate the epigenetic changes along the model of GBC carcinogenesis represented by the sequence gallstone disease -> dysplasia -> GBC in Chile, the country with the highest incidence of GBC worldwide.

Más información

Título según WOS: Epigenome-Wide Analysis of Methylation Changes in the Sequence of Gallstone Disease, Dysplasia, and Gallbladder Cancer
Título según SCOPUS: ID SCOPUS_ID:85101376789 Not found in local SCOPUS DB
Título de la Revista: HEPATOLOGY
Volumen: 73
Editorial: LIPPINCOTT WILLIAMS & WILKINS
Fecha de publicación: 2021
Página de inicio: 2293
Página final: 2310
DOI:

10.1002/HEP.31585
Notas: ISI, SCOPUS