Abstract

is a multifactor disease resulting from the interaction of multiple genetic and environmental factors, such as sedentary lifestyle and the diet of the individual. On the other hand, diabetes mellitus is a complex metabolic disease that involves multiple organ systems, and it is characterized by chronic hyperglycemia due to a defect in the glycemic regulation as a result of insulin secretion, its actions or both. Combined, these diseases provide the concept of diabesity, which is defined as the alloy of type II diabetes and obesity, with or without associated risk factors. Obesity encourages diabetes, and both diseases are considered two global epidemics of the modern age that show no signs of decreasing their prevalence and contribute to cardiovascular diseases, the leading cause of death worldwide. This chapter is aimed to characterize both physiopathology and impact on health to understand their management and treatment.