Treatment of blepharospasm and Meige's syndrome with botulinum toxin: Experience and follow-up in 18 cases Tratamiento del Blefaroespasmo y Síndrome de Meige con toxina botulínica. Experiencia y seguimiento en 18 casos

Chana, P; Kunstman, C; Benavldes O.; Tapia-Nunez, J; Munoz D.S.

Keywords: patient, treatment, scale, human, male, toxin, adult, female, duration, article, satisfaction, controlled, clinical, blepharospasm, study, response, syndrome, a, rating, botulinum, Meige


Treatment with botulinum toxin (BT) is a good therapeutic alternative for patients with blepharospasm and Meige's syndrome. We report follow up results of 18 patients with blepharospasm and Meige's syndrome treated with botulinum toxin, to asses therapy response. 67 injection sessions were performed with a mean dose of 40.2 ± 26.5 Ul. The duration of effect was 120 ± 50 days and the global assessment of the results on a scale from 0 to 4 (0 no results to 4 very good results) was an average of 3.1 ± 0.72. We can say that botulinum toxin therapy was good or very good in 14 (77.7%) patients with blepharospasm and Meige's Syndrome. Only 3 cases (16.6%) had significative complications, reversible in all cases.

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Título de la Revista: Revista Ecuatoriana de Neurologia
Volumen: 17
Número: 1-3
Editorial: Fundacion para la difusion neurologica en Ecuador - FUNDINE
Fecha de publicación: 2008