Oil bodies as a potential microencapsulation carrier for astaxanthin stabilisation and safe delivery

Acevedo, F; Rubilar, M.; Jofre, I.; Villarroel M.; Navarrete P.; Esparza M.; Romero F.; Vilches, EA; Acevedo, V; Shene C.

Abstract

Astaxanthin (AST) is a valued molecule because of its high antioxidant properties. However, AST is extremely sensitive to oxidation, causing the loss of its bioactive properties. The purposes of this study were to define conditions for microencapsulating AST in oil bodies (OB) from Brassica napus to enhance its oxidative stability, and to test the bioactivity of the microencapsulated AST (AST-M) in cells. Conditions for maximising microencapsulation efficiency (ME) were determined using the Response Surface Methodology, obtaining a high ME (>99%). OB loaded with AST showed a strong electrostatic repulsion in a wide range of pH and ionic strengths. It was found that AST-M exposed to air and light was more stable than free AST. In addition, the protective effect of AST against intracellular ROS production was positively influenced by microencapsulation in OB. These results suggest that OB offer a novel option for stabilising and delivering AST.

Más información

Título según WOS: Oil bodies as a potential microencapsulation carrier for astaxanthin stabilisation and safe delivery
Título según SCOPUS: Oil bodies as a potential microencapsulation carrier for astaxanthin stabilisation and safe delivery
Título de la Revista: JOURNAL OF MICROENCAPSULATION
Volumen: 31
Número: 5
Editorial: TAYLOR & FRANCIS LTD
Fecha de publicación: 2014
Página de inicio: 488
Página final: 500
Idioma: English
DOI:

10.3109/02652048.2013.879931

Notas: ISI, SCOPUS