Ketogenic diet ameliorates dysferlinopathy phenotype by promoting mitochondrial function in in vitro and in vivo models of the disease.

Juilo Cesar Cardenas; Pablo Caviedes, Jorge Bevilacqua

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Fecha de publicación: 2020
Objetivos: Objective: To study the effects of glucose, β-hydroxybutyrate, and acetoacetate on dysferlin-deficient myoblast cell lines and primary cells from patient biopsies. Also, to test the effects of KD on mitochondrial function and in vivo motor function of dysferlin-deficient mice.
Año de Inicio/Término: 2020-2021
Financiamiento/Sponsor: Jain Foundation,Seattle,WA EEUU
Rol del Usuario: COINVESTIGADOR(A)

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