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Carolina Llanos Muñoz

Profesor Asociado

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

Autoimmunity; Neonatal Lupus; Systemic Lupus Erythematosus; Role of Dendritic cells in infectious, inflammatory and autoimmune disease.; Role of Fc receptors in the onset of autoimmune diseases; Role of the pMHC complex half life in the immunological synapsis; hormonas y enfermedades autoinmunes; sindrome antifosfolipido; enfermedades autoinmunes; Systemic Lupus Erythematosus. Clinical and molecular aspects; Rheumatoid Arthritis. Imunopathogenesis. Genetics

Medico, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2000

Profesor Asociado Full Time

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE (PUC)

Medicina

Santiago, Chile

2012 - A la fecha

Académico Full Time

Pontificia Universidad Catolica de Chile

Chile

2012 - A la fecha

Director de Tesis de Pregrado para optar a grado de bioquímico Fabián Vega

Mejor Investigador Joven

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Chile, 2014

Investigador joven con mejor productividad y proyecciones en la Escuela de Medicina de la P. Universidad Católica de Chile


Heme-Oxygenase-1 Is Decreased in Circulating Monocytes and Is Associated With Impaired Phagocytosis and ROS Production in Lupus Nephritis Cuitino, Loreto; Obreque, Javiera; Gajardo-Meneses, Patricia; Villarroel, Alejandra; Crisostomo, Natalia; San Francisco, Ignacio F.; Valenzuela, Rodrigo.; Mendez, Gonzalo P.; Llanos, Carolina Article ISI SCOPUS Frontiers in Immunology (2019)
Innate Immune Cells' Contribution to Systemic Lupus Erythematosus Herrada, Andres A.; Escobedo, Noelia; Iruretagoyena, Mirentxu; Valenzuela, Rodrigo A.; Burgos, Paula I.; Cuitino, Loreto; Llanos, Carolina Article ISI SCOPUS Frontiers in Immunology (2019)
The Prevalence of Rheumatoid Arthritis in Chile: A Nationwide Study Performed as Part of the National Health Survey Durán, Josefina; Massardo, Loreto; Llanos, Carolina; Iacobelli, Sergio; Burgos, Paula; Cisternas, Marcela; Iruretagoyena, Mirentxu; Armstrong, Macarena; Aguilera, Raquel; Radrigán, Francisco; Martinez, María Eugenia; Passi-Solar, Alvaro; Riedemann, Pablo; Crisóstomo, Natalia; Cifuentes, Camila; Hagedorn, Lucero; Cisternas, Alvaro; Vasquez, Nancy; Margozzini, Paula Article JOURNAL OF RHEUMATOLOGY (2019)
First Latin American clinical practice guidelines for the treatment of systemic lupus erythematosus: Latin American Group for the Study of Lupus (GLADEL, Grupo Latino Americano de Estudio del Lupus)-Pan-American League of Associations of Rheumatology (PANLAR) Pons-Estel B.A.; Bonfa E.; Soriano E.R.; Cardiel M.H.; Izcovich A.; Popoff F.; Criniti J.M.; Vásquez G.; Massardo L.; Duarte M.; Barile-Fabris L.A.; García M.A.; Amigo M.-C.; Espada G.; Catoggio L.J.; Sato E.I.; Levy R.A.; Acevedo Vásquez E.M.; Chacón-DÍaz R.; Galarza-Maldonado C.M.; Iglesias Gamarra A.J.; Molina J.F.; Neira O.; Silva C.A.; Vargas Peña A.; Gómez-Puerta J.A.; Scolnik M.; Pons-Estel G.J.; Ugolini-Lopes M.R.; Savio V.; Drenkard C.; Alvarellos A.J.; Ugarte-Gil M.F.; Babini A.; Cavalcanti A.; Cardoso Linhares F.A.; Haye Salinas M.J.; Fuentes-Silva Y.J.; Montandon De Oliveira E Silva A.C.; Eraso Garnica R.M.; Herrera Uribe S.; Gómez-Martín D.; Robaina Sevrini R.; Quintana R.M.; Gordon S.; Fragoso-Loyo H.; Rosario V.; Saurit V.; Appenzeller S.; Dos Reis Neto E.T.; Cieza J.; González Naranjo L.A.; González Bello Y.C.; Collado M.V.; Sarano J.; Retamozo S.; Sattler M.E.; Gamboa-Cárdenas R.V.; Cairoli E.; Conti S.M.; Amezcua-Guerra L.M.; Silveira L.H.; Borba E.F.; Pera M.A.; Alba Moreyra P.B.; Arturi V.; Berbotto G.A.; Gerling C.; Gobbi C.A.; Gervasoni V.L.; Scherbarth H.R.; Brenol J.C.T.; Cavalcanti, F; Costallat L.T.L.; da Silva N.A.; Monticielo O.A.; Seguro L.P.C.; Xavier R.M.; Llanos C.; Montúfar Guardado R.A.; Garcia De La Torre I.; Pineda C.; Portela Hernández M.; Danza A.; Guibert-Toledano M.; Reyes G.L.; Acosta Colman M.I.; Aquino A.M.; Mora-Trujillo C.S.; Muñoz-Louis R.; García Valladares I.; Orozco M.C.; Burgos P.I.; Betancur G.V.; Alarcón G.S. Article ISI SCOPUS Annals of the Rheumatic Diseases (2018)
Autologous tolerogenic dendritic cells derived from monocytes of systemic lupus erythematosus patients and healthy donors show a stable and immunosuppressive phenotype Obreque, J; Vega, F; Torres, A; Cuitino, L; Mackern-Oberti, JP; Viviani, P; Kalergis, A; Llanos, C Article ISI SCOPUS Immunology (2017)
Induction of HO-1 expression in monocytes might prevent kidney damage in lupus nephritis (LN) Cuitino, Loreto; Obreque, Javiera; Gajardo-Meneses, Patricia; Crisostomo, Natalia; Torres, Andy; Kalergis, Alexis M.; Llanos, Carolina. Article ANNALS OF THE RHEUMATIC DISEASES (2017)
Modulating the function of the immune system by thyroid hormones and thyrotropin Jara, Evelyn L.; Muñoz-Durango, Natalia; Llanos, Carolina; Fardella, Carlos; González, Pablo A.; Bueno, Susan M.; Kalergis, Alexis M.; Riedel, Claudia A. Article ISI SCOPUS IMMUNOLOGY LETTERS (2017)
Modulating the function of the immune system by thyroid hormones and thyrotropin. Jara, Evelyn L; Muñoz-Durango, Natalia; Llanos, Carolina; Fardella, Carlos; González, Pablo A; Bueno, Susan M; Kalergis, Alexis M; Riedel, Claudia A Article Immunology letters (2017)
Flagellate Erythema in a Case of Paraneoplastic Dermatomyositis. Manriquez, Juan; Acle, Renata; Llanos, Carolina Article Journal of clinical rheumatology => practical reports on rheumatic & musculoskeletal diseases (2016)
Carbon monoxide inhibits T cell activation in target organs during systemic lupus erythematosus Mackern-Oberti, JP; Obreque J., Mendez; GP, Llanos C. Article Clinical and Experimental Immunology (2015)
Carbon monoxide inhibits T cell activation in target organs during systemic lupus erythematosus Mackern-Oberti, JP; Obreque J.; Mendez, GP; Llanos, C.; Kalergis, AM Article ISI SCOPUS Clinical and Experimental Immunology (2015)
Contribution of dendritic cells to the autoimmune pathology of systemic lupus erythematosus. Mackern-Oberti, Juan P; Llanos, Carolina; Riedel, Claudia A; Bueno, Susan M; Kalergis, Alexis M Article Immunology (2015)
Role of dendritic cells in the initiation, progress and modulation of systemic autoimmune diseases. Mackern-Oberti, Juan Pablo; Llanos, Carolina; Vega, Fabián; Salazar-Onfray, Flavio; Riedel, Claudia A; Bueno, Susan M; Kalergis, Alexis M Article Autoimmunity reviews (2015)
Role of dendritic cells in the initiation, progress and modulation of systemic autoimmune diseases. Mackern-Oberti JP; Llanos C; Vega F; Salazar-Onfray F; Riedel CA; Bueno SM; Kalergis AM Article Autoimmune Rev (2015)
Heme oxygenase-1 as a target for the design of gene and pharmaceutical therapies for autoimmune diseases Mackern-Oberti J.P.; Riquelme, S. A.; Llanos, C.; Schmidt, C. B.; Simon, T; Anegon, I; Jara, E; Riedel, C. A.; Bueno, S. M.; Kalergis, A.M. Article SCOPUS Current Gene Therapy (2014)
Heme Oxygenase-1 as a Target for the Design of Gene and Pharmaceutical Therapies for Autoimmune Diseases Macker-Oberti, JP; Riquelme, SA; Llanos, C; Schmidt, CB; Simon T, Anegon; I, Jara; E, Riedel; C, Bueno; S, Kalergis Article CURRENT GENE THERAPY (2014)
Heme Oxygenase-1 as a Target for the Design of Gene and Pharmaceutical Therapies for Autoimmune Diseases. Mackern-Oberti, Juan Pablo; Riquelme, Sebastian A; Llanos, Carolina; Schmidt, Camila B; Simon, Thomas; Anegon, Ignacio; Jara, Evelyn; Riedel, Claudia A; Bueno, Susan M; Kalergis, Alexis M Article Current gene therapy (2014)
Heme Oxygenase-1 as a Target for the Design of Gene and Pharmaceutical Therapies for Autoimmune Diseases. Mackern-Oberti, Juan Pablo; Riquelme, Sebastian A; Llanos, Carolina; Schmidt, Camila B; Simon, Thomas; Anegon, Ignacio; Jara, Evelyn; Riedel, Claudia A; Bueno, Susan M; Kalergis, Alexis M Article Current gene therapy (2014)
Letter to the Editor in response to the article "Preventing congenital neonatal heart block in offspring of mothers with anti-SSA/Ro and SSB/La antibodies: a review of published literature and registered clinical trials." by Gleicher N, Elkayam U, Autoimm Costedoat-Chalumeau, Nathalie; Izmirly, Peter; Clancy, Robert; Saxena, Amit; Wahren-Herlenius, Marie; Silverman, Earl; Brucato, Antonio; Boutjdir, Mohamed; Khamashta, Munther; Llanos, Carolina; Pisoni, Cecilia N; Friedman, Deborah M; Phoon, Colin K L; Buyon, Jill P Article Autoimmunity reviews (2014)
Targeting dendritic cell function during systemic autoimmunity to restore tolerance. Mackern-Oberti JP; Vega F; Llanos C; Bueno SM; Kalergis AM: Article Int J Mol Sci (2014)
Carbon monoxide exposure improves immune function in lupus-prone mice Mackern-Oberti, JP; Llanos C., Carreno; LJ, Riquelme; SA, Jacobelli; SH, Anegon I. Article Immunology (2013)
Carbon monoxide exposure improves immune function in lupus-prone mice Mackern-Oberti, JP; Llanos, C.; Carreno, LJ; Riquelme, SA; Jacobelli, SH; Anegon, I; Kalergis, AM Article ISI SCOPUS Immunology (2013)
Carbon monoxide exposure improves immune function in lupus-prone mice Mackern-Oberti, JP; Llanos, C; Carreno, LJ; Riquelme, SA; Jacobelli, SH; Anegon, I; Kalergis, AM Article IMMUNOLOGY (2013)
Carbon monoxide exposure improves immune function in lupus-prone mice Mackern-Oberti, JP; Llanos, C; Carreno, LJ; Riquelme, SA; Jacobelli, SH; Anegon, I; Kalergis, AM Article IMMUNOLOGY (2013)
Carbon monoxide exposure improves immune function in lupus-prone mice. Mackern-Oberti, Juan P; Llanos, Carolina; Carreño, Leandro J; Riquelme, Sebastián A; Jacobelli, Sergio H; Anegon, Ignacio; Kalergis, Alexis M Article Immunology (2013)
Tolerogenic dendritic cells as a therapy for treating lupus. Llanos, Carolina; Mackern-Oberti, Juan Pablo; Vega, Fabián; Jacobelli, Sergio H; Kalergis, Alexis M Article Clinical immunology (Orlando, Fla.) (2013)
Tolerogenic dendritic cells as a therapy for treating lupus. Llanos, Carolina; Mackern-Oberti, Juan Pablo; Vega, Fabián; Jacobelli, Sergio H; Kalergis, Alexis M Article Clinical immunology (Orlando, Fla.) (2013)
Anatomical and pathological findings in hearts from fetuses and infants with cardiac manifestations of neonatal lupus Llanos, C.; Friedman D.M.; Saxena, A; Izmirly P.M.; Tseng C.-E.; Dische R.; Abellar R.G.; Halushka M.; Clancy R.M.; Buyon J.P. Article ISI SCOPUS Rheumatology (United Kingdom) (2012)
Anatomical and pathological findings in hearts from fetuses and infants with cardiac manifestations of neonatal lupus Llanos C., Friedman D.M.; Saxena A., Izmirly P.M.; Tseng C.-E., Dische R.; Abellar R.G., Halushka M.; Clancy R.M., Buyon J.P. Article Rheumatology (2012)
Anatomical and pathological findings in hearts from fetuses and infants with cardiac manifestations of neonatal lupus. Llanos, Carolina; Friedman, Deborah M; Saxena, Amit; Izmirly, Peter M; Tseng, Chung-E; Dische, Renata; Abellar, Rosanna G; Halushka, Marc; Clancy, Robert M; Buyon, Jill P Article Rheumatology (Oxford, England) (2012)
Haem oxygenase 1 expression is altered in monocytes from patients with systemic lupus erythematosus Herrada A.A., Llanos C.; Mackern-Oberti J.P., Carreño L.J.; Henriquez C, Gómez R.S.; Gutiérrez M.A., Anegon I.; Jacobelli S.H., Kalergis A.M. Article Immunology (2012)
Haem oxygenase 1 expression is altered in monocytes from patients with systemic lupus erythematosus Herrada A.A.; Llanos, C.; Mackern-Oberti J.P.; Carreño L.J.; Henriquez, C; Gómez R.S.; Gutiérrez M.A.; Anegon, I; Jacobelli S.H.; Kalergis, A.M. Article ISI SCOPUS Immunology (2012)
Haem oxygenase 1 expression is altered in monocytes from patients with systemic lupus erythematosus. Herrada, Andrés A; Llanos, Carolina; Mackern-Oberti, Juan P; Carreño, Leandro J; Henriquez, Carla; Gómez, Roberto S; Gutierrez, Miguel A; Anegon, Ignacio; Jacobelli, Sergio H; Kalergis, Alexis M Article Immunology (2012)
Haem oxygenase 1 expression is altered in monocytes from patients with systemic lupus erythematosus. Herrada, Andrés A; Llanos, Carolina; Mackern-Oberti, Juan P; Carreño, Leandro J; Henriquez, Carla; Gómez, Roberto S; Gutierrez, Miguel A; Anegon, Ignacio; Jacobelli, Sergio H; Kalergis, Alexis M Article Immunology (2012)
Heme oxygenase-1 expression were decreased in monocytes from Systemic Lupus Erithematosus patients Mackern, J; Llanos C.; Herrada, A; Leandro, C; Gomez R.; Anegon I.; Jacobelli S.; Kalergis A. Article JOURNAL OF IMMUNOLOGY (2012)
Maternal Use of Hydroxychloroquine Is Associated With a Reduced Risk of Recurrent Anti-SSA/Ro-Antibody-Associated Cardiac Manifestations of Neonatal Lupus Izmirly P.M., Costedoat-Chalumeau; N, Pisoni C.N.; Khamashta M.A., Kim M.Y.; Saxena A., Friedman D.; Llanos C., Piette J.-C. Article CIRCULATION (2012)
Maternal Use of Hydroxychloroquine Is Associated With a Reduced Risk of Recurrent Anti-SSA/Ro-Antibody-Associated Cardiac Manifestations of Neonatal Lupus Izmirly P.M.; Costedoat-Chalumeau, N; Pisoni C.N.; Khamashta M.A.; Kim M.Y.; Saxena, A; Friedman, D; Llanos, C.; Piette J.-C.; Buyon J.P. Article ISI SCOPUS Circulation (2012)
Maternal use of hydroxychloroquine is associated with a reduced risk of recurrent anti-SSA/Ro-antibody-associated cardiac manifestations of neonatal lupus. Izmirly, Peter M; Costedoat-Chalumeau, Nathalie; Pisoni, Cecilia N; Khamashta, Munther A; Kim, Mimi Y; Saxena, Amit; Friedman, Deborah; Llanos, Carolina; Piette, Jean-Charles; Buyon, Jill P Article Circulation (2012)
Association of the Idiotype: Antiidiotype Antibody Ratio With the Efficacy of Intravenous Immunoglobulin Treatment for the Prevention of Recurrent Autoimmune-Associated Congenital Heart Block Routsias, JG; Kyriakidis, NC; Friedman, DM; Llanos, C; Clancy, R; Moutsopoulos, HM; Buyon J.; Tzioufas, AG Article ARTHRITIS AND RHEUMATISM (2011)
Association of the Idiotype: Antiidiotype Antibody Ratio With the Efficacy of Intravenous Immunoglobulin Treatment for the Prevention of Recurrent Autoimmune-Associated Congenital Heart Block Routsias, JG; Kyriakidis, NC; Friedman, DM; Llanos, C.; Clancy, R; Moutsopoulos, HM; Buyon J.; Tzioufas, AG Article ISI SCOPUS Arthritis and Rheumatism (2011)
Association of the Idiotype=> Antiidiotype Antibody Ratio With the Efficacy of Intravenous Immunoglobulin Treatment for the Prevention of Recurrent Autoimmune-Associated Congenital Heart Block Routsias, JG; Kyriakidis, NC; Friedman, DM; Llanos C., Clancy; R, Moutsopoulos; HM, Buyon J.; Tzioufas, AG Article Arthritis and Rheumatism (2011)
Contribution of dendritic cell/T cell interactions to triggering and maintaining autoimmunity Llanos, C.; Carreno, LJ; Kalergis, AM Article ISI SCIELO SCOPUS Biological Research (2011)
Contribution of dendritic cell/T cell interactions to triggering and maintaining autoimmunity Llanos C.; Carreno, LJ; Kalergis, AM Article BIOLOGICAL RESEARCH (2011)
Contribution of dendritic cell/T cell interactions to triggering and maintaining autoimmunity Llanos C., Carreno; LJ, Kalergis AM Article Biological Research (2011)
Contribution of dendritic cell/T cell interactions to triggering and maintaining autoimmunity. Llanos, Carolina; Carreño, Leandro J; Kalergis, Alexis M Article Biological research (2011)
Genetic and Pharmacological Modulation of Dendritic Cell-T Cell Interactions as a Therapeutic Strategy for Systemic Lupus Erythematosus Llanos C.; Carreno, LJ; Gutierrez, MA; Riedel, CA; Jacobelli, SH; Kalergis, AM Article CURRENT GENE THERAPY (2011)
Genetic and pharmacological modulation of dendritic cell-T cell interactions as a therapeutic strategy for systemic lupus erythematosus. Llanos, Carolina; Carreño, Leandro J; Gutierrez, Miguel A; Riedel, Claudia A; Jacobelli, Sergio H; Kalergis, Alexis M Article Current gene therapy (2011)
Maternal and Fetal Factors Associated With Mortality and Morbidity in a Multi-Racial/Ethnic Registry of Anti-SSA/Ro-Associated Cardiac Neonatal Lupus Izmirly, PM; Saxena, A; Kim, MY; Wang, D; Sahl, SK; Llanos, C; Friedman D.; Buyon, JP Article CIRCULATION (2011)
Maternal and Fetal Factors Associated With Mortality and Morbidity in a Multi-Racial/Ethnic Registry of Anti-SSA/Ro-Associated Cardiac Neonatal Lupus Izmirly, PM; Saxena A., Kim; MY, Wang; D, Sahl; SK, Llanos C.; Friedman D., Buyon Article CIRCULATION (2011)
Maternal and Fetal Factors Associated With Mortality and Morbidity in a Multi-Racial/Ethnic Registry of Anti-SSA/Ro-Associated Cardiac Neonatal Lupus Izmirly, PM; Saxena, A; Kim, MY; Wang D.; Sahl, SK; Llanos, C.; Friedman, D; Buyon, JP Article ISI SCOPUS Circulation (2011)
Anatomic and Pathologic Findings in Hearts from Fetuses and Infants with Cardiac Manifestations of Neonatal Lupus Llanos C.; Clancy, RM; Abellar, R; Buyon, JP; Friedman, DM Article SCANDINAVIAN JOURNAL OF IMMUNOLOGY (2010)
Cutaneous manifestations of neonatal lupus and risk of subsequent congenital heart block. Izmirly, Peter M; Llanos, Carolina; Lee, Lela A; Askanase, Anca; Kim, Mimi Y; Buyon, Jill P Article Arthritis and rheumatism (2010)
Evaluation of fetuses in a study of intravenous immunoglobulin as preventive therapy for congenital heart block: Results of a multicenter, prospective, open-label clinical trial. Friedman, Deborah M; Llanos, Carolina; Izmirly, Peter M; Brock, Brigit; Byron, John; Copel, Joshua; Cummiskey, Karen; Dooley, Mary Anne; Foley, Jill; Graves, Cornelia; Hendershott, Colleen; Kates, Richard; Komissarova, Elena V; Miller, Michelle; Paré, Emmanuelle; Phoon, Colin K L; Prosen, Tracy; Reisner, Dale; Ruderman, Eric; Samuels, Philip; Yu, Jerry K; Kim, Mimi Y; Buyon, Jill P Article Arthritis and rheumatism (2010)
Evaluation of the risk of anti-SSA/Ro-SSB/La antibody-associated cardiac manifestations of neonatal lupus in fetuses of mothers with systemic lupus erythematosus exposed to hydroxychloroquine. Izmirly, Peter M; Kim, Mimi Y; Llanos, Carolina; Le, Phuong U; Guerra, Marta M; Askanase, Anca D; Salmon, Jane E; Buyon, Jill P Article Annals of the rheumatic diseases (2010)
Antibody reactivity to alpha-enolase in mothers of children with congenital heart block. Llanos, Carolina; Chan, Edward K L; Li, Songqing; Abadal, Grant X; Izmirly, Peter; Byrne, Caroline; Clancy, Robert M; Buyon, Jill P Article The Journal of rheumatology (2009)
Prospective evaluation of fetuses with autoimmune-associated congenital heart block followed in the PR Interval and Dexamethasone Evaluation (PRIDE) Study. Friedman, Deborah M; Kim, Mimi Y; Copel, Joshua A; Llanos, Carolina; Davis, Claudine; Buyon, Jill P Article The American journal of cardiology (2009)
Recurrence rates of cardiac manifestations associated with neonatal lupus and maternal/fetal risk factors. Llanos, Carolina; Izmirly, Peter M; Katholi, Margaret; Clancy, Robert M; Friedman, Deborah M; Kim, Mimi Y; Buyon, Jill P Article Arthritis and rheumatism (2009)
Could single-nucleotide polymorphisms (SNPs) affecting the tumour necrosis factor promoter be considered as part of rheumatoid arthritis evolution? Aguillón, Juan C; Cruzat, Andrea; Aravena, Octavio; Salazar, Lorena; Llanos, Carolina; Cuchacovich, Miguel Article Immunobiology (2006)
Prostate cancer cell proliferation in vitro is modulated by antibodies against glucose-regulated protein 78 isolated from patient serum Gonzalez-Gronow M.; Cuchacovich, M; Llanos, C; Urzua C.; Gawdi G.; Pizzo, SV Article CANCER RESEARCH (2006)
Prostate cancer cell proliferation in vitro is modulated by antibodies against glucose-regulated protein 78 isolated from patient serum Gonzalez-Gronow, M; Cuchacovich M.; Llanos, C.; urzua c; Gawdi, G; Pizzo, SV Article ISI SCOPUS CANCER RESEARCH (2006)
Systemic vasculitis associated with Fasciola hepatica infection Llanos, C; Soto, L; Sabugo, F; Gallegos I.; Valenzuela O.; Verdaguer J.; Cuchacovich, M Article SCANDINAVIAN JOURNAL OF RHEUMATOLOGY (2006)
Systemic vasculitis associated with Fasciola hepatica infection Llanos, C.; Soto L.; Sabugo, F; Gallegos, I.; Valenzuela O.; Verdaguer J.; Cuchacovich M. Article ISI SCOPUS SCANDINAVIAN JOURNAL OF RHEUMATOLOGY (2006)
Tumour necrosis factor (TNF)alpha-308 G/G promoter polymorphism and TNF alpha levels correlate with a better response to adalimumab in patients with rheumatoid arthritis Cuchacovich, M; Soto, L; Edwardes, M.; Gutierrez, M; Llanos, C; Pacheco, D.; Sabugo, F; Alamo, M; Fuentealba, C; Villanueva L.; Gatica H.; Schiattino, I; Salazar, L; Catalan, D; Valenzuela O. Article SCANDINAVIAN JOURNAL OF RHEUMATOLOGY (2006)
Tumour necrosis factor (TNF)alpha-308 G/G promoter polymorphism and TNF alpha levels correlate with a better response to adalimumab in patients with rheumatoid arthritis Cuchacovich M.; Soto L.; Edwardes, M; Gutiérrez M; Llanos, C.; Pacheco, D.; Sabugo, F; Alamo, M; Fuentealba, C; Villanueva, L; Gatica H.; Schiattino I.; Salazar, L; Catalan, D; Valenzuela O. Article ISI SCOPUS SCANDINAVIAN JOURNAL OF RHEUMATOLOGY (2006)
[Emergent therapies for rheumatoid arthritis]. Aguillón, Juan C; Cruzat, Andrea; Contreras-Levicoy, Juan; Dotte, Andrés; Pesce, Bárbara; Aravena, Octavio; Salazar, Lorena; Catalán, Diego; Abello, Paula; Aguirre, Adam; Llanos, Carolina; Cuchacovich, Miguel Article Revista mÃ©dica de Chile (2005)
Anti-tumor necrosis factor-? therapy augments dipeptidyl peptidase IV activity and decreases autoantibodies to GRP78/BIP and phosphoglucose isomerase in patients with rheumatoid arthritis Mavropoulos J.C.; Cuchacovich M.; Llanos, C.; AguillÃ³n J.C.; Gatica H.; Pizzo S.V.; Gonzalez-Gronow M. Article SCOPUS JOURNAL OF RHEUMATOLOGY (2005)
Anti-tumor necrosis factor-alpha therapy augments dipeptidyl peptidase IV activity and decreases autoantibodies to GRP78/BIP and phosphoglucose isomerase in patients with rheumatoid arthritis Mavropoulos, JC; Cuchacovich M.; Llanos, C.; Aguillón JC; Gatica H.; Pizzo, SV; Gonzalez-Gronow, M Article ISI JOURNAL OF RHEUMATOLOGY (2005)
Anti-tumor necrosis factor-alpha therapy augments dipeptidyl peptidase IV activity and decreases autoantibodies to GRP78/BIP and phosphoglucose isomerase in patients with rheumatoid arthritis. Mavropoulos, John C; Cuchacovich, Miguel; Llanos, Carolina; Aguillón, Juan C; Gatica, Hector; Pizzo, Salvatore V; Gonzalez-Gronow, Mario Article The Journal of rheumatology (2005)
Multiple imputation procedures allow the rescue of missing data: An application to determine serum tumor necrosis factor (TNF) concentration values during the treatment of rheumatoid arthritis patients with anti-TNF therapy Schiattino I.; Villegas, R; Cruzat, A; Cuenca J.; Salazar, L; Aravena, O; Pesce B,; Catalan, D; Llanos, C.; Cuchacovich M.; Aguillón JC Article ISI SCIELO SCOPUS BIOLOGICAL RESEARCH (2005)
Rituximab (anti-CD20 monoclonal antibody) for refractory systemic lupus erythematosus. Report of one case Sabugo, F; Llanos, C.; Soto L.; Gutierrez J.; Cuchacovich M. Article ISI Revista médica de Chile (2005)
Autologous tolerogenic dendritic cells derived from monocyte of systemic lupus erythematosus patientes and healthy controls show a stable and immunosuppresive phenotype Obreque, Javiera; Vega, Fabian; Torres, Andy; Cuitino, Loreto; Mackern, Juan; Viviani, Paola; Kalergis, Alexis; Llanos, Carolina Article IMMUNOLOGY (0)
Carbon monoxide inhibits T cell activation in target organs during SLE. Mackern-Oberti JP; Obreque J; Méndez G; Llanos C; Kalergis AM Article Clin Exp Imm (0)
Cutaneous manifestations of neonatal lupus and risk of subsequent congenital heart block. Izmirly PM; Llanos C; Lee LA; Askanese A; Kim MY; Buyon JP Article Arthritis and Rheumatism (0)
Prospective evaluation of fetuses with autoimmune-associated congenital heart block followed in the PR Interval and Dexamethasone Evaluation (PRIDE) Study. Friedman DM; Kim MY; Copel JA; Llanos C; Davis C; Buyon JP Article American Journal of Cardiology (0)
Recurrence rates of cardiac manifestations associated with neonatal lupus and maternal/fetal risk factors. Llanos C; Izmirly PM; Katholi M; Clancy RM; Friendman DM; Kim MY; Buyon JP Article Arthritis and Rheumatism (0)


HO-1 Expression in Monocytes Might Regulate Kidney Damage in Lupus Nephritis Patients Cuitino, L; Obreque, J; Gajardo-Meneses, P; Mendez, GP; Kalergis, AM; Llanos, C Abstract ISI ARTHRITIS RHEUMATOLOGY (2017)
INDUCTION OF HO-1 EXPRESSION IN MONOCYTES MIGHT PREVENT KIDNEY DAMAGE IN LUPUS NEPHRITIS (LN) Cuitino, L; Obreque, J; Gajardo-Meneses, P; Crisostomo, N; Torres, A; Kalergis, AM; Llanos, C Abstract ISI ANNALS OF THE RHEUMATIC DISEASES (2017)
IGG4-RELATED DISEASE, REPORT OF 10 CASES Gutierrez, M; Mansilla, B; Herrera, A; Schweitzer, F; Álvarez, A; Pedreros, C; Jara, A; Tagle, R; Gonzalez, S; Llanos, C; Mezzano, V; Sandoval, P Abstract ISI (2016)
Heme oxygenase-1 expression were decreased in monocytes from Systemic Lupus Erithematosus patients Mackern, J; Llanos, C.; Herrada, A; Leandro, C; Gomez, R; Anegon, I; Jacobelli, S.; Kalergis, A Abstract ISI JOURNAL OF IMMUNOLOGY (2012)
Anatomic and Pathologic Findings in Hearts from Fetuses and Infants with Cardiac Manifestations of Neonatal Lupus Llanos, C.; Clancy, RM; Abellar, R; Buyon, JP; Friedman, DM Abstract ISI SCANDINAVIAN JOURNAL OF IMMUNOLOGY (2010)
Tumor necrosis factor-alpha levels gurrelate with a better response to adalimumab in patients with rheumatoid arthritis Cuchacovich M.; Soto L.; Gutiérrez M; Llanos, C.; Sabugo, F; Pacheco, D.; Alamos, M; Fuentealba, C; Villanueva, L; Gatica H.; Schiattino I.; Salazar, L; Catalan, D; Valenzuela O.; SALAZAR ONFRAY F; Aguillon, J. Abstract ISI ANNALS OF THE RHEUMATIC DISEASES (2006)
Dendritic cells pulsed with type II bovine collagen modulate the murine collagen induced arthritis. Salazar, LE; Aravena, OA; Abello P; Aguirre A.; Catalan, D; Llanos, C.; Sabugo, F; González F; González C; Cuchacovich M.; Aguillón JC Abstract ISI CLINICAL IMMUNOLOGY (2005)
TNF-alpha-308 G/G promoter polymorphism correlates with a better response to adalimumab in patients with rheumatoid arthritis Cuchacovich M.; Soto L.; Edwardes, M; Suissa, S; Gutiérrez M; Llanos, C.; Sabugo, F; Pacheco, D.; Alamo, M; Fuentealba, C; Villanueva, L; Gatica H.; Salazar, L; Valenzuela O.; Salazar F.; Aguillon, J. Abstract ISI ANNALS OF THE RHEUMATIC DISEASES (2005)
Tumor necrosis factor-alpha-308 G/G promoter polymorphism correlates with a better response to adalimumab in patients with rheumatoid arthritis. Cuchacovich M.; Soto L.; Edwardes, M; Gutiérrez M; Llanos, C.; Pacheco, D.; Sabugo, F; Alamo, M; Fuentealba, C; Villanueva, L; Gatica H.; Schiattino I.; Salazar, L; Catalan, D; Valenzuela O.; SALAZAR ONFRAY F; Aguillón JC Abstract ISI ARTHRITIS AND RHEUMATISM (2005)
Interaction between REM sleep homeostasis, wakefulness and non-REM sleep, in sleep deprivation protocols Rodríguez A.; Llanos, C.; Molina, E.; Ocampo-Garces, A; Vivaldi, E Abstract ISI JOURNAL OF PHYSIOLOGY-LONDON (2000)
Length of REM sleep episodes during selective intermittent deprivation of REM sleep Llanos, C.; Molina, E.; Rodríguez A.; Ocampo-Garces, A; Vivaldi, EA Abstract ISI JOURNAL OF PHYSIOLOGY-LONDON (2000)


Flagellate Erythema in a Case of Paraneoplastic Dermatomyositis Manríquez, J; Acle, R; Llanos, C EditorialMaterial ISI SCOPUS JCR: Journal of Clinical Rheumatology (2016)


Letter to the Editor in response to the article Preventing congenital neonatal heart block in offspring of mothers with anti-SSA/Ro and SSB/La antibodies: A review of published literature and registered clinical trials. by Gleicher N, Elkayam U, Autoimmun Rev. 2013 Sep;12(11):1039-45 Costedoat-Chalumeau, N; Lzmirly, P; Clancy, R; Saxena, A; Wahren-Herlenius, M; Silverman, E; Brucato, A; Boutjdir, M; Khamashta, M; Llanos, C.; Pisoni, CN; Friedman, DM; Phoon, CKL; Buyon, JP Letter ISI AUTOIMMUNITY REVIEWS (2014)


Contribution of dendritic cells to the autoimmune pathology of systemic lupus erythematosus Mackern-Oberti, JP; Llanos, C.; Riedel, CA; Bueno, SM; Kalergis, AM Review ISI SCOPUS Immunology (2015)
Role of dendritic cells in the initiation, progress and modulation of systemic autoimmune diseases Mackern-Oberti, JP; Llanos, C.; Vega, F; SALAZAR ONFRAY F; Riedel, CA; Bueno, SM; Kalergis, AM Review ISI SCOPUS Autoimmunity Reviews (2015)
Targeting Dendritic Cell Function during Systemic Autoimmunity to Restore Tolerance Mackern-Oberti, JP; Vega, F; Llanos, C.; Bueno, SM; Kalergis, AM Review ISI SCOPUS INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2014)
Tolerogenic dendritic cells as a therapy for treating lupus Llanos, C.; Mackern-Oberti, JP; Vega, F; Jacobelli, SH; Kalergis, AM Review ISI SCOPUS Clinical Immunology (2013)
Genetic and Pharmacological Modulation of Dendritic Cell-T Cell Interactions as a Therapeutic Strategy for Systemic Lupus Erythematosus Llanos, C.; Carreno, LJ; Gutierrez MA; Riedel, CA; Jacobelli, SH; Kalergis, AM Review ISI CURRENT GENE THERAPY (2011)
Could single-nucleotide polymorphisms (SNPs) affecting the tumour necrosis factor promoter be considered as part of rheumatoid arthritis evolution? Aguillón JC; Cruzat, A; Aravena, O; Salazar, L; Llanos, C.; Cuchacovich M. Review ISI IMMUNOBIOLOGY (2006)
Emergent therapies for rheumatoid arthritis Aguillón JC; Cruzat, A; Contreras-Levicoy, J; Dotte, A; Pesce B,; Aravena, O; Salazar, L; Catalan, D; Abello P; Aguirre A.; Llanos, C.; Cuchacovich M. Review ISI Revista médica de Chile (2005)

Carolina Llanos

Profesor Asociado

Inmunología Clínica y Reumatología

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

Carolina Llanos

Associate Professor

Pontificia Universidad Católica de Chile

Santiago, Chile

Diego Catalán

Profesor Asistente

Programa Disciplinario de Inmunología

Universidad de Chile

Santiago, Chile

JUAN AGUILLON

PROFESSOR

IMMUNOLOGY PROGRAM

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

Alexis Kalergis

Full Professor

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE. FACULTAD DE CIENCIAS BIOLÓGICAS

Santiago, Chile

Lorena Salazar

Academico

Instituto Cs Biomédicas

Universidad Autónoma de Chile

Santiago, Chile

Claudia Riedel

Full Professor

Life Sciences

Universidad Andres Bello

Santiago, Chile

Loreto Cuitiño

Investigador Asociado

Oftalmología

Hospital Clínico Universidad de Chile

229788866, Chile

Susan Bueno

Profesor Asociado

Genética Molecular y Microbiología

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

Fabián Vega

Investigador postdoctoral

Oftalmología

Universidad de Chile

Santiago, Chile

Lilian Soto

Rheumatologist

Medicine

CLINICAL HOSPITAL OF UNIVERSIDAD DE CHILE

Santiago, Chile

Maria Sabugo

Medico Reumatologo

Medicina

UNIVERSIDAD DE CHILE HOSPITAL CLÍNICO

Santiago, Chile

OCTAVIO ARAVENA

Director Científico

I+D+i

MEDICEL SA

Santiago, Chile

Leandro Carreño

Profesor Asistente

Instituto de Ciencias Biomédicas

Universidad de Chile

Santiago, Chile

Paula Abello

Rodrigo Valenzuela

Postdoctorado

Oftalmología

Universidad de Chile

Santiago, Chile

Bárbara Pesce

Profesora Asistente

ICBM

Universidad de Chile

Santiago, Chile

Mirentxu Iruretagoyena

Jefe Seccion Inmunologia

Laboratorio Clinico

Clinica Alemana de Santiago

Santiago, Chile

IVAN GALLEGOS

PATHOLOGIST, LABORATORY DIRECTOR

PATHOLOGY

HOSPITAL CLINICO DE UNIVERSIDAD DE CHILE

SANTIAGO, Chile

María Villarroel

Médico Anátomo-Patólogo

Anatomía Patológica

Red de Salud UC Christus / Pontificia Universidad Católica de Chile

Santiago, Chile

Flavio Salazar

Profesor titular

Instituto de ciencias biomédicas

Universidad de Chile

SANTIAGO, Chile

Evelyn Jara

Docente/Investigador

Ciencias Básicas

Universidad Santo Tomás

Temuco, Chile

Rodrigo Villegas

Jefe Programa de Bioestadística

Bioestadística

Universidad de Chile - Facultad de Medicina

Santiago, Chile

Natalia Muñoz

Estudiante de Doctorado y Jefe Alterno_Proyecto COPEC-UC R772

Genética Molecular y Microbiología

Pontificia Universidad Católica de Chile

Santiago, Chile

Jimena Cuenca

Investigador/profesor

Facultad de Medicina

Universidad de Los Andes

Santiago, Chile

Noelia Escobedo

Profesor Asistente

Facultad de Ciencias de la Salud

Universidad Autónoma de Chile

Talca, Chile

Carolina Llanos Muñoz

Líneas de Investigación

Educación

Medico, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2000

Experiencia Académica

Profesor Asociado Full Time

Experiencia Profesional

Académico Full Time

Formación de Capital Humano

Premios y Distinciones

Mejor Investigador Joven

Article (75)

Abstract (11)

EditorialMaterial (1)

Letter (1)

Review (7)