Application of the cytogenetic techniques multiple FISH and multiple BAND. Report of five cases Múltiple FISH y múltiple BAND: Técnicas de citogenética molecular en cinco casos

Castillo-Taucher, S; Pardo V A; Fuentes S. A.M.; Paulos M. A.

Keywords: fluorescence, hybridization, humans, leukemia, human, male, genetics, aged, methodology, adult, female, pattern, chromosome, infant, article, child, aberrations, banding, map, preschool, mapping, myeloid, middle, in, Child,, case, Karyotyping, report, Leukemia,, Situ, aberration, Hybridization,

Abstract

The techniques of multiple FISH (M-FlSH) or fluorescence in situ hybridization with different color assignment for all and each of the human chromosomes, and multiple BAND (M-BAND) or hybridization with different color assignment for each chromosomal band, allow the identification of some alterations that would not be possible to distinguish with classical banding techniques, like the origin of the chromosomal material that constitutes a (non identifiable) marker chromosome or confirming the constitution of the multiple and simultaneous aberrations that occur in cancer cells. We communicate five complex cytogenetic cases that benefited by the employment of this diagnostic strategy, allowing to corroborate or reformulate a previous given conclusion.

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Título según SCOPUS: Application of the cytogenetic techniques multiple FISH and multiple BAND. Report of five cases [Múltiple FISH y múltiple BAND: Técnicas de citogenética molecular en cinco casos]
Título de la Revista: REVISTA MEDICA DE CHILE
Volumen: 130
Número: 5
Editorial: SOC MEDICA SANTIAGO
Fecha de publicación: 2002
Página de inicio: 511
Página final: 518
Idioma: Spanish
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-0346678527&partnerID=q2rCbXpz
Notas: SCOPUS