Human metapneumovirus as hospitalization cause in children under 3 years old with acute respiratory infections during 2004 Metapneumovirus humano como causa de hospitalización en niños bajo 3 años de edad, con infección respiratoria aguda, durante el año 2004
Keywords: isolation, chile, purification, infections, infection, transcription, disease, chain, virus, humans, human, male, genetics, polymerase, newborn, female, infant, article, child, tract, respiratory, acute, hospitalization, preschool, reverse, metapneumovirus, studies, study, Reaction, Child,, and, prospective, virology, Infant,, Paramyxoviridae, Transcriptase
Human metapneumovirus was detected in 15 of 123 children (12%) younger than 3 years of age hospitalized for treatment of acute respiratory infection between July and November 2004. The virus was detected by RT-PCR directly from nasopharyngeal swabs and/or from supernatants after cell culture. Children infected with hMPV were mostly younger than one year of age (67%), all presenting with fever and cough. The main cause for hospitalization was the need for oxygen therapy (73%). Four hMPV positive children had an identifiable co-morbid condition but had a similar clinical evolution when compared to previously healthy infants. Chest radiography showed an increase in interstitial infiltrates with focal consolidation in 6 children. Obstructive bronchial syndrome and bronchiolitis, with or without pneumonia, were the most frequent diagnosis associated with hMPV positivity. A rapid and sensitive diagnostic method is required to improve diagnosis and treatment of these patients. © 2007 Sociedad Chilena de Infectología.
|Título de la Revista:||Revista Chilena de Infectologia|
|Editorial:||Sociedad Chilena de Infectología|
|Fecha de publicación:||2007|
|Página de inicio:||19|