A systematic study of antibacterial silver nanoparticles: efficiency, enhanced permeability, and cytotoxic effects

Azocar, Manuel I.; Tamayo, Laura; Vejar, Nelson; Gómez, Grace; Zhou, Xiangrong; Thompsom, George; CERDA, ENRIQUE; Kogan Marcelo J.; Salas, Edison; Páez, Maritza A

Abstract

We report here a systematic study of the antibacterial behavior of silver nanoparticles coated with fatty acids (oleic: AgNP-O, linoleic: AgNP-L, and palmitic acids: AgNP-P) in water. We have found remarkable differences in their capability to penetrate bacteria cell over a broader range of particle size of similar to 4-96 nm compared to previously reported work, and a variable toxicity depending on the particles size. Our results indicate that silver nanoparticles stabilized with oleic acid showed clear advantages in antibacterial activity, penetration inside the bacteria cells, cytotoxicity, time effectiveness, efficiency, and stability against light.

Más información

Título según WOS: A systematic study of antibacterial silver nanoparticles: efficiency, enhanced permeability, and cytotoxic effects
Título según SCOPUS: A systematic study of antibacterial silver nanoparticles: efficiency, enhanced permeability, and cytotoxic effects
Título de la Revista: JOURNAL OF NANOPARTICLE RESEARCH
Volumen: 16
Número: 9
Editorial: Springer
Fecha de publicación: 2014
Idioma: English
URL: http://link.springer.com/10.1007/s11051-014-2465-4
DOI:

10.1007/s11051-014-2465-4

Notas: ISI, SCOPUS