Withanolides from three species of the genus Deprea (Solanaceae). Chemotaxonomical considerations

Casero C.N.; Oberti J.C.; Orozco C.I.; Cardenas, A; Brito, I; Barboza G.E.; Nicotra V.E.

Keywords: Chemotaxonomic markers; Deprea; Solanaceae; Withanolides

Abstract

Nine withanolides were isolated from the aerial parts of Deprea bitteriana, Deprea cuyacensis, and Deprea zamorae. D. bitteriana yielded two withaphysalins, D. cuyacensis gave two 13,14-seco withaphysalins, while D. zamorae yielded five physangulidines. The compounds were fully characterized by a combination of spectroscopic methods (1D and 2D NMR and MS). All compounds isolated from D. bitteriana and D. cuyacensis were obtained as epimeric mixtures at C-18. The structure of physangulidine D was confirmed by X-ray diffraction analysis. The skeletons found in this research support the chemotaxonomical position of the genus Deprea in the tribe Physalideae.

Más información

Título según SCOPUS: Withanolides from three species of the genus Deprea (Solanaceae). Chemotaxonomical considerations
Título de la Revista: PHYTOCHEMISTRY
Volumen: 110
Editorial: PERGAMON-ELSEVIER SCIENCE LTD
Fecha de publicación: 2015
Página de inicio: 83
Página final: 90
Idioma: English
DOI:

10.1016/j.phytochem.2014.11.015

Notas: SCOPUS