Management of the potential organ donor

Bugedo G.; Bravo S.; Romero C.; Castro R.

Keywords: brain death, organ transplantation, Living donors, Tissue donors


Solid organ transplantation is limited by donor availability. The loss of brain function produces hemodynamic, respiratory, hormonal and metabolic changes that lead to hypotension and organ dysfunction. Management of a potential donor is similar to any critically ill patient. Cardiovascular stability and protective ventilatory support must be pursued, aimed at minimizing the local and systemic inflammatory response that is triggered by brain death. There is no consensus on protocols for hormonal supplementation. The administration of vasopressin analogues and steroids may be beneficial under certain conditions. Appropriate medical management helps to optimize the function of different organs prior to transplantation. This may increase the number of harvested organs and improve their functional outcome in the recipient.

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Título según WOS: Management of the potential organ donor
Título de la Revista: REVISTA MEDICA DE CHILE
Volumen: 142
Número: 12
Editorial: Sociedad Médica de Santiago
Fecha de publicación: 2014
Página de inicio: 1584
Página final: 1593
Idioma: Spanish
Notas: ISI