Antioxidant Activity of Selected Chemical Constituents of Quinchamalium chilensis.

Rita Aquino, Teresa Mencherini, Patrizia Picerno, Philippe Christen, Consuelo Castro, Pamela Villarroel, Carla Delporte, Orlando Muñoz

Keywords: antioxidant activity, quinchamalium chilensis, flavonoid glycosides, total phenolic content


Phytochemical investigation of the aerial parts of Quinchamalium chilensis Mol. (Santalaceae) resulted in the isolation and identification of four flavonol glycosides, quercetin-3-O-β-D-glucopyranosyl-(1→2)-[α-L-rhamnopyranosyl-(1→6)]-β-D glucopyranoside (1), kaempferol-3-O-β-D-glucopyranosyl-(1→2)-[α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside (2), quercetin-3-O-xylosyl-(1→2)-[α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside (3) and rutin (4), as well as one flavananone glycoside, pinocembroside (5). The compounds were identified by 1D- and 2D-NMR experiments, mass spectrometry and UV spectra by comparison with those reported in literature. These compounds were isolated for the first time from the leaves of Q. chilensis. The antioxidant properties of the extract were investigated using DPPH and ferric reducing antioxidant potential (FRAP) assays. Total phenolic content was determined by the Folin-Ciocalteau method. Significant relationship between antioxidant capacity and total phenolic content was found, indicating that phenolic compounds are the major contributors to the antioxidant properties of this plant.

Más información

Título de la Revista: Journal of Pharmaceutical Sciences and Nanotechnology
Volumen: 8
Número: 1
Fecha de publicación: 2015
Página de inicio: 2775
Página final: 2778
Idioma: English

MS ID: IJPSN-10-24-14-

Notas: Impact Factor: TBA, Cited half-life: Growing rapidly (2008-2015), Acceptance rate: 75%, Average time to first decision: 30 days, Frequency and Format: Quarterly print and online publication since 2006,