Opportunistic infections in pediatric HIV infection: A study of 74 autopsy cases from Latin America

WEISSENBACHER, M; PERUGA, A; Drut, R; Quijano, G; Greco, MA; Ridaura, C; deLeonBojorge, B; Siminovich, M; Anderson, V; Mayoral, PV; Menezes, D; Gutierrez, C


The present report describes opportunistic infections found at 74 autopsies of pediatric HIV/AIDS patients performed at several hospitals in Latin American countries. Fungal infections were the most common (53 cases), Candida sp. (39.18%) and Pneumocystis carinii (20.27%) being the most frequently recognized. Other fungal diseases included histoplasmosis, aspergillosis, and cryptococcosis. Viral infections were present in 31 cases, 38.7% being due to cytomegalovirus. Other viruses recognized included herpes simplex and adenovirus. Additional opportunistic infections were due to Mycobacterium avium-intracellulare, toxoplasmosis, and tuberculosis. Nonspecific bacterial bronchopneumonia was present in II cases. Cytomegalovirus and P. carinii coinfection was the most common association found. In this series patients died at a younger age (72% at or younger than 2 year old) and there was a slightly higher number of cases of histoplasmosis and brain toxoplasmosis than in other previously published series of infants and children.

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Título según WOS: ID WOS:A1997XF25800005 Not found in local WOS DB
Volumen: 17
Número: 4
Editorial: Taylor & Francis
Fecha de publicación: 1997
Página de inicio: 569
Página final: 576


Notas: ISI