dsDNA Sensing Capabilities of Metallopolymers Electrochemically Deposited from Ruthenium-Pyrrole and - Thiophene Complexes

de Valle, M. A.; Gonzalez, B.; Espinosa-Bustos, C.; Ramirez, A. M. R.; Gacitua, M.; hernandez, L. A.

Abstract

In the current work, a study is presented based on the variation of the monomer unit (thiophene or pyrrole) at electrochemically polymerizable ruthenium complexes, evaluating their possible applications in the field of biosensors to detect dsDNA. For both complexes ([Ru(p-cymene)(C4H4S)(2)](2+) and [Ru(p-cymene)(C5H4NH)(2)](2+)), the metallopolymer is deposited on platinum electrodes displaying voltamperometric responses consistent with expected polymer including the corresponding Ru-III -> II redox signa. The subsequent evaluation of these electrodeposits, in the presence and absence of dsDNA, demonstrated the essential role that monomer play when an application of these modified electrodes is needed. The use of thiophene as a polymerizable produces a more intense analyte-electrode interaction, with an electrode about 1.7 more sensitive to dsDNA compared to that of pyrrole.

Más información

Título según WOS: dsDNA Sensing Capabilities of Metallopolymers Electrochemically Deposited from Ruthenium-Pyrrole and - Thiophene Complexes
Título según SCOPUS: dsDNA sensing capabilities of metallopolymers electrochemically deposited from ruthenium-pyrrole and-thiophene complexes
Título de la Revista: INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE
Volumen: 14
Número: 8
Editorial: ESG
Fecha de publicación: 2019
Página de inicio: 8131
Página final: 8140
Idioma: English
DOI:

10.20964/2019.08.64

Notas: ISI, SCOPUS