Effect of Minocycline on the Durability of Dentin Bonding Produced with Etch-and-Rinse Adhesives

Loguercio, A. D.; Stanislawczuk, R.; Malaquias, P.; Gutierrez, M. F.; Bauer, J.; Reis, A.


Objectives: To evaluate the effect of minocycline and chlorhexidine pretreatment of acid-etched dentin on the longevity of resin-dentin bond strength (mu TBS) and nanoleakage of two-step etch-and-rinse adhesives. Methods: Before application of Prime Bond NT and Adper Single Bond 2 in occlusal dentin, the dentin surfaces were treated with 37% phosphoric acid, rinsed, air-dried, and rewetted with water (control group), 2% minocycline, or 2% chlorexidine digluconate. Composite buildups were constructed incrementally, and specimens were longitudinally sectioned to obtain bonded sticks (0.8 mm(2)) to be tested in tension (0.5 mm/min) immediately or after 24 months of water storage. For nanoleakage, two specimens of each tooth/period were immersed in the silver nitrate solution, photo-developed, and polished with SiC paper for analysis under energy-dispersive X-ray spectroscopy/scanning electron microscopy. Results: Reductions of the mu TBS and increases in the nanoleakage were observed for both adhesives when the rewetting procedure was performed with water. Stable bonds were observed for the 2% minocycline and 2% chlorexidine digluconate groups after 24 months. Conclusions: The use of 2% minocycline as pretreatment of acid-etched dentin is one alternative to retard the degradation of resin-dentin interfaces over a 24-month period as well as 2% chlorexidine digluconate.

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Título según WOS: ID WOS:000386153800006 Not found in local WOS DB
Título de la Revista: OPERATIVE DENTISTRY
Volumen: 41
Número: 5
Fecha de publicación: 2016
Página de inicio: 511
Página final: 519


Notas: ISI