Article ISI SCOPUS
RHEUMATOLOGY  (2020)

Aberrant MUC1 accumulation in salivary glands of Sjogren's syndrome patients is reversed by TUDCA in vitro

Castro I, Albornoz N, Aguilera S, Barrera MJ, González S, Núñez M, Carvajal P, Jara D, Lagos C, Molina C, Urzúa U, Hermoso MA, González MJ.

Abstract

Objectives. Xerostomia in SS patients has been associated with low quality and quantity of salivary mucins, which are fundamental for the hydration and protection of the oral mucosa. The aim of this study was to evaluate if cytokines induce aberrant mucin expression and whether tauroursodeoxycholic acid (TUDCA) is able to counteract such an anomaly.

Más información

Título según WOS: Aberrant MUC1 accumulation in salivary glands of Sjogren's syndrome patients is reversed by TUDCA in vitro
Título según SCOPUS: Aberrant MUC1 accumulation in salivary glands of Sjögren's syndrome patients is reversed by TUDCA in vitro
Título de la Revista: RHEUMATOLOGY
Volumen: 59
Número: 4
Editorial: OXFORD UNIV PRESS
Fecha de publicación: 2020
Página de inicio: 742
Página final: 753
Idioma: English
DOI:

10.1093/RHEUMATOLOGY/KEZ316
Notas: ISI, SCOPUS