The de novo production of halogenated hydroquinone metabolites by the Andean-Patagonian white-rot fungus Phylloporia boldo
Keywords: Drosophilin A – drosophilin A methyl ether – organohalogens
The production of halogenated hydroquinone metabolites such as drosophilin A, drosophilin A methyl ether and chloroneb was investigated in the Andean-Patagonian fungus Phylloporia boldo. These chlorinated compounds were detected in both fruiting bodies and living cultures. Gas chromatography–mass spectrometry (GC-MS) quantification of these molecules was performed in liquid media giving similar values in comparison to previous reports. We observed the concentration of drosophilin A, drosophilin A methyl ether and chloroneb increased in liquid culture supplemented with KCl. Furthermore, chlorinated hydroquinone compounds were not detected using liquid media supplemented with KBr. Instead, brominated aromatic molecules were observed and quantified by gas chromatography–mass spectrometry. We consider these results are relevant for the use of these halogenating microorganisms in biotransformation processes.
|Título de la Revista:||Current Research in Environmental & Applied Mycology (Journal of Fungal Biology)|
|Fecha de publicación:||2020|
|Página de inicio:||198|
|Financiamiento/Sponsor:||FONDECYT regular 1190652; MEC 2019 (MEC80190048)|