Atf6 inhibitors and uses thereof

Alfaro, Jennifer; Belmar, Sebastian; Nuñez, Gonzalo; Pujala, Brahmam; Sathe, Balaji; Bernales, Sebastian; Chakravarty, Sarvajit; Thakral, Pooja; Patidar, Rajesh

Keywords: isr, atf6, Integrated Stress Response


Compounds as inhibitors of Activating Transcription Factor 6 (ATF6) are provided. The compounds may find use as therapeutic agents for the treatment of diseases or disorders mediated by ATF6 and may find particular use in the treatment of viral infections, neurodegenerative diseases, vascular diseases, or cancer.

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Fecha de publicación: 2019