Laterality of motor cortical function measured by transcranial magnetic stimulation threshold tracking

Shibuya, Kazumoto; Park, Susanna B.; Howells, James; Huynh, William; Noto, Yu-ichi; Shahrizaila, Nortina; Matamala, Jose M.; Vucic, Steve; Kiernan, Matthew C.


Introduction: Threshold tracking paired-pulse transcranial magnetic stimulation (TTTMS) examines cortical function and is useful for diagnosis of motor neuron disorders. Differences in cortical function have been identified between dominant and non-dominant limbs using constant stimulus methods, but they remain unclear, potentially due to methodological differences. In this study we aimed to clarify differences in cortical function between dominant and non-dominant limbs using TTTMS. Methods: Single-pulse TMS, TTTMS, and nerve conduction studies were performed in 25 healthy, right-handed participants by recording from the abductor pollicis brevis muscle. Results: There were no side-to-side differences observed in resting motor threshold, motor evoked potential (MEP) amplitude, MEP latency, central motor conduction time, cortical silent period, short-interval intracortical inhibition and facilitation, compound muscle action potential (CMAP) amplitude, CMAP latency, F-wave latency, or neurophysiological index. Conclusions: These findings suggest that, when using TTTMS, there are no differences in cortical function between dominant and non-dominant hemispheres. Muscle Nerve55: 424-427, 2017

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Título según WOS: ID WOS:000395648000021 Not found in local WOS DB
Título de la Revista: MUSCLE NERVE
Volumen: 55
Número: 3
Editorial: John Wiley & Sons Inc.
Fecha de publicación: 2017
Página de inicio: 424
Página final: 426


Notas: ISI