Gallstones, Body Mass Index, C-Reactive Protein, and Gallbladder Cancer: Mendelian Randomization Analysis of Chilean and European Genotype Data

Ponce, Carol Barahona; Scherer, Dominique; Brinster, Regina; Boekstegers, Felix; Marcelain, Katherine; Garate-Calderon, Valentina; Muller, Bettina; Toro, Gonzalo; Retamales, Javier; Barajas, Olga; Ahumada, Monica; Morales, Erik; Rojas, Armando; Sanhueza, Veronica; Loader, Denisse; et. al.

Abstract

Background and Aims Gallbladder cancer (GBC) is a neglected disease with substantial geographical variability: Chile shows the highest incidence worldwide, while GBC is relatively rare in Europe. Here, we investigate the causal effects of risk factors considered in current GBC prevention programs as well as C-reactive protein (CRP) level as a marker of chronic inflammation.

Más información

Título según WOS: Gallstones, Body Mass Index, C-Reactive Protein, and Gallbladder Cancer: Mendelian Randomization Analysis of Chilean and European Genotype Data
Título de la Revista: HEPATOLOGY
Volumen: 73
Número: 5
Editorial: WILEY-BLACKWELL
Fecha de publicación: 2021
Página de inicio: 1783
Página final: 1796
DOI:

10.1002/HEP.31537

Notas: ISI