Therapeutic Efficacy of Human Monoclonal Antibodies against Andes Virus Infection in Syrian Hamsters

Brandi N Williamson; Joseph Prescott; Jose L Garrido; Raymond A Alvarez; Heinz Feldmann; Maria I Barría

Abstract

Andes virus, an orthohantavirus endemic to South America, causes severe hantavirus cardiopulmonary syndrome associated with human-to-human transmission. No approved treatments or vaccines against this virus are available. We show that a combined treatment with 2 monoclonal antibodies protected Syrian hamsters when administered at midstage or late-stage disease.

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Título de la Revista: EMERGING INFECTIOUS DISEASES
Volumen: 27
Número: 10
Editorial: CENTER DISEASE CONTROL
Fecha de publicación: 2021
Página de inicio: 2707
Página final: 2710
Notas: Emerg Infect Dis. 2021 Oct;27(10):2707-2710. doi: 10.3201/eid2710.210735.