Phytochemical Constituents, Biological Activities, and Health-Promoting Effects of the Melissa officinalis

Sharifi-Rad, Javad; Quispe, Cristina; Herrera-Bravo, Jesus; Akram, Muhammad; Abbaass, Wafa; Semwal, Prabhakar; Painuli, Sakshi; Konovalov, Dmitry Alekseevich; Alfred, Mary Angelia; Kumar, Nanjangud Venkatesh Anil; Imran, Muhammad; Nadeem, Muhammad; Sawicka, Barbara; Pszczolkowski, Piotr; Bienia, Bernadetta; et. al.


Medicinal plants are being used worldwide for centuries for their beneficial properties. Some of the most popular medicinal plants belong to the Melissa genus, and different health beneficial effects have already been identified for this genus. Among these species, in particular, the Melissa officinalis L. has been reported as having many biological activities, such as antioxidant, antimicrobial, antitumour, antiviral, antiallergic, anti-inflammatory, and also flatulence inhibiting effects. The beneficial properties of the Melissa officinalis, also known as "lemon balm herb", can be related to the bioactive compounds such as terpenoids, alcohols, rosmarinic acid, and phenolic antioxidants which are present in the plant. In this updated review, the botanical, geographical, nutritional, phytochemical, and traditional medical aspects of M. officinalis have been considered as well as in vitro and in vivo and clinically proven therapeutic properties have been reviewed with a special focus on health-promoting effects and possible perspective nutraceutical applications. To evidence the relevance of this plant in the research and completely assess the context, a literature quantitative research analysis has been performed indicating the great interest towards this plant for its beneficial properties.

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Título según WOS: ID WOS:000842829000001 Not found in local WOS DB
Título de la Revista: Oxidative Medicine and Cellular Longevity
Volumen: 2021
Editorial: HINDAWI LTD
Fecha de publicación: 2021


Notas: ISI