Sedentary time play a moderator role in the relationship between physical fitness and brain-derived neurotrophic factor in children. A pilot study
Abstract
Aim: Despite some advances, there are many controversies concerning brain-derived neurotrophic factor (BDNF) and its relationships with variables related to physical fitness and sedentary time, especially in children. The aim of the study was to explore the moderating role of sedentary time on the association between physical fitness and BDNF. Therefore, this study will add to the perspective of understanding how much time children may spend being sedentary with no deleterious influence on the positive as-sociation between physical fitness and BDNF.Methods: This cross-sectional study included 44 children aged between 6 and 11 years (9.02 +/- 1.43) from a public school in Porto Alegre, Brazil. Cardiorespiratory fitness (CRF) was determined by the 6-min walk/ run test, and muscular strength was determined through the lower limb strength test (LLS). Sedentary time was assessed through accelerometers, and blood samples were collected to determine serum BDNF levels (z score). Moderation analysis was performed using the PROCESS macro adjusted for sex, age, somatic maturation, waist circumference, and socioeconomic level.Results: Sedentary time moderates the relationship between CRF and BDNF, such that children should spend less than 511 minutes per day sedentary to achieve the benefits of CRF in BDNF concentrations.Conclusion: Sedentary time plays a significant moderating role in the relationship between CRF and BDNF. Therefore, to promote brain health in children, both increasing physical fitness and reducing sedentary time might be encouraged.(c) 2022 The Society of Chinese Scholars on Exercise Physiology and Fitness. Published by Elsevier (Singapore) Pte Ltd. This is an open access article under the CC BY-NC-ND license (http:// creativecommons.org/licenses/by-nc-nd/4.0/).
Más información
Título según WOS: | ID WOS:000901777100002 Not found in local WOS DB |
Título de la Revista: | JOURNAL OF EXERCISE SCIENCE & FITNESS |
Volumen: | 21 |
Número: | 1 |
Editorial: | ELSEVIER SINGAPORE PTE LTD |
Fecha de publicación: | 2023 |
Página de inicio: | 119 |
Página final: | 124 |
DOI: |
10.1016/j.jesf.2022.11.004 |
Notas: | ISI |