Cancer and brassinosteroids: Mechanisms of action, SAR and future perspectives

Lorca, Marcos; Cabezas, David; Araque, Ileana; Teran, Andres; Hernandez, Santiago; Mellado, Marco; Espinoza, Luis; Mella, Jaime


Brassinosteroids are plant hormones whose main function is to stimulate plant growth. However, they have been studied for their biological applications in humans. Brassinosteroid compounds have displayed an important role in the study of cancer pathology and show potential for developing novel anticancer drugs. In this review we describe the relationship of brassinosteroids with cancer with focus on the last decade, the mechanisms of cytotoxic activity described to date, and a structure-activity relationship based on the available information.

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Título según WOS: ID WOS:000910146600001 Not found in local WOS DB
Título de la Revista: STEROIDS
Volumen: 190
Editorial: Elsevier Science Inc.
Fecha de publicación: 2023


Notas: ISI