STABILITY STUDY OF PRAVASTATIN UNDER HYDROLYTIC CONDITIONS ASSESSED BY HPLC

Brain-Isasi, S; Requena C.; Alvarez-Lueje, A

Abstract

In this work an HPLC stability-indicating method was developed and applied to study the hydrolytic behavior of pravastatin in different pHs and temperatures. From the system suitability test, the selected chromatographic conditions were a C-18 column, acetonitrile-30 mmol L-1 phosphate buffer solution pH 2 (28:72) as mobile phase, 40

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Título según WOS: STABILITY STUDY OF PRAVASTATIN UNDER HYDROLYTIC CONDITIONS ASSESSED BY HPLC
Título según SCOPUS: Stability study of pravastatin under hydrolytic conditions assessed by HPLC
Título según SCIELO: STABILITY STUDY OF PRAVASTATIN UNDER HYDROLYTIC CONDITIONS ASSESSED BY HPLC
Título de la Revista: JOURNAL OF THE CHILEAN CHEMICAL SOCIETY
Volumen: 53
Número: 4
Editorial: 2013
Fecha de publicación: 2008
Página de inicio: 1684
Página final: 1688
Idioma: English
DOI:

10.4067/S0717-97072008000400010

Notas: ISI, SCIELO, SCOPUS