Complete nucleotide sequence analysis of a Dengue-1 virus isolated on Easter Island, Chile

Caceres, C; Yung V.; Araya, P; Tognarelli J.; Villagra E.; Vera L.; fernandez, j

Abstract

Dengue-1 viruses responsible for the dengue fever outbreak in Easter Island in 2002 were isolated from acute-phase sera of dengue fever patients. In order to analyze the complete genome sequence, we designed primers to amplify contiguous segments across the entire sequence of the viral genome. RT-PCR products obtained were cloned, and complete nucleotide and deduced amino acid sequences were determined. This report constitutes the first complete genetic characterization of a DENV-1 isolate from Chile. Phylogenetic analysis shows that an Easter Island isolate is most closely related to Pacific DENV-1 genotype IV viruses. © 2008 Springer-Verlag.

Más información

Título según WOS: Complete nucleotide sequence analysis of a Dengue-1 virus isolated on Easter Island, Chile
Título según SCOPUS: Complete nucleotide sequence analysis of a Dengue-1 virus isolated on Easter Island, Chile
Título de la Revista: ARCHIVES OF VIROLOGY
Volumen: 153
Número: 10
Editorial: Springer-Verlag Wien
Fecha de publicación: 2008
Página de inicio: 1967
Página final: 1970
Idioma: English
URL: http://link.springer.com/10.1007/s00705-008-0200-0
DOI:

10.1007/s00705-008-0200-0

Notas: ISI, SCOPUS