Thermal Injury Protocol to Study Healing, With and Without Infection, in Guinea Pig (Cavia porcellus) Model

Jessica Salvo; Carolina Schencke; Mónica Pávez; Carlos Veuthey; Mariano del Sol

Keywords: animal model, cavia porcellus, Wound healing.


Experimental healing studies in humans are complex and difficult to replicate in vitro. Hence, animal models are needed to study the different stages involved. The guinea pig (Cavia porcellus) is a model close to human physiology, including the lack of vitamin C synthesis, a precursor of collagen fibers for healing. The thermal injury in this animal makes it possible to study all the stages of healing, taking few days to show tissue repair in the processes with and without localized infection. The aim of this work was to systematize an experimental guinea pig (Cavia porcellus) animal model protocol for studies on healing with and without localized infection.

Más información

Título de la Revista: International Journal of Morphology
Volumen: 41(4)
Editorial: Dr. Mariano Del Sol. Universidad de la Frontera, Chile.
Fecha de publicación: 2023
Página de inicio: 1053
Página final: 1057
Idioma: Ingles
Notas: Scielo WoS